Scored…PPI #network to catalyze genomic interpretation http://www.Nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.4083.html >500k links from lit. mining; up weights small-scale expt
Hum. Longevity
http://www.nature.com/nm/journal/v22/n11/abs/nm.4191.html
"Classification and characterization of
microsatellite instability across 18 cancer types" by Hause,
Pritchard, Shendure and Salipante from Nature Medicine, 2016
Characterization of microsatellite instability across 18 cancer types http://www.nature.com/nm/journal/v22/n11/abs/nm.4191.html Classifier finds cancer-associated #MSI loci
#IHECpapers rollout http://www.Cell.com/consortium/ihec Gr8 work! incl. #privacy, normal breast epigenetics, ETG links, deconvolution, #allelic activity
TWiEVO 9: How to crash your gene drive
July 5, 2016
Hosts: Nels Elde and Vincent Racaniello
Guest: Jim Bull
Nels and Vincent speak with Jim Bull about the results of genetic models which suggest that the evolution of inbreeding in response to lethal gene drive might make population control difficult to achieve.
https://bioconductor.org/packages/release/bioc/html/variancePartition.html
new tool in psychencode meeting
Distribution of #miRNA expression across human tissues
http://nar.oxfordjournals.org/content/44/8/3865 Atlas of ~1400 RNAs in at least 1 of 61 tissues; 143 in all
#Frustration in biomolecules
https://www.cambridge.org/core/journals/quarterly-reviews-of-biophysics/article/frustration-in-biomolecules/DECEA176849986FC11DB079C1EB4B24A Reviews the field: how large molecules pay a local price to achieve global stability