Archive for the ‘SciLit’ Category

A primer on deep learning in genomics | Nature Genetics

Monday, October 21st, 2019

A primer on deep learning in genomics | Nature Genetics
https://www.nature.com/articles/s41588-018-0295-5
James Zou, Mikael Huss, Abubakar Abid, Pejman Mohammadi, Ali Torkamani & Amalio Telenti
Nature Genetics volume 51, pages12–18 (2019)

Vinclozolin induced epigenetic transgenerational inheritance of pathologies and sperm epimutation biomarkers for specific diseases

Sunday, October 20th, 2019

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202662

Vinclozolin induced epigenetic transgenerational inheritance of pathologies and sperm epimutation biomarkers for specific diseases Eric Nilsson,Stephanie E. King,Margaux McBirney,Deepika
Kubsad,Michelle Pappalardo,Daniel Beck,Ingrid Sadler-Riggleman,Michael K. Skinner

Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs

Monday, October 14th, 2019

https://www.nature.com/articles/s41592-019-0575-8

Published: 07 October 2019

Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs

Tristan Bepler, Andrew Morin, Micah Rapp, Julia Brasch, Lawrence Shapiro, Alex J. Noble & Bonnie Berger

Nature Methods (2019)

High Time for Human Height

Saturday, October 12th, 2019

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269490/

Perit Dial Int. 2014 Nov-Dec; 34(7): 685–686.
doi: 10.3747/pdi.2014.00272
PMCID: PMC4269490
PMID: 25520478
Olivier Devuyst, Deputy Editor

Genome partitioning of genetic variation for height from 11,214 sibling pairs. – PubMed – NCBI

Saturday, October 12th, 2019

https://www.ncbi.nlm.nih.gov/pubmed/17924350

Am J Hum Genet. 2007 Nov;81(5):1104-10. Epub 2007 Oct 1.
Genome partitioning of genetic variation for height from 11,214 sibling pairs. Visscher PM1, Macgregor S, Benyamin B, Zhu G, Gordon S, Medland S, Hill WG, Hottenga JJ, Willemsen G, Boomsma DI, Liu YZ, Deng HW, Montgomery GW, Martin NG.

The Future of Genetic Studies of Complex Human Diseases | Science

Saturday, October 12th, 2019

https://science.sciencemag.org/content/273/5281/1516

Neil Risch, Kathleen Merikangas
proposed gwas

Complement Factor H Polymorphism in Age-Related Macular Degeneration | Science

Saturday, October 12th, 2019

https://science.sciencemag.org/content/308/5720/385.long

Robert J. Klein1, Caroline Zeiss2,*, Emily Y. Chew3,*, Jen-Yue Tsai4,*, Richard S. Sackler1, Chad Haynes1, Alice K. Henning5, John Paul SanGiovanni3, Shrikant M. Mane6, Susan T. Mayne7, Michael B. Bracken7, Frederick L. Ferris3, Jurg Ott1, Colin Barnstable2, Josephine Hoh7,†

see https://plu.mx/mtsinai/u/rklein

Complement Factor H Polymorphism in Age-Related Macular Degeneration

Saturday, October 12th, 2019

https://en.wikipedia.org/wiki/Factor_H

Complement Factor H Polymorphism in Age-Related Macular Degeneration

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1512523/

gene name Cfh

RFMix: A Discriminative Modeling Approach for Rapid and Robust Local-Ancestry Inference: The American Journal of Human Genetics

Tuesday, October 8th, 2019

https://www.cell.com/ajhg/fulltext/S0002-9297(13)00289-9#%20

Diabetes and RACE A Historical Perspective

Sunday, October 6th, 2019

ethnicity & diabetes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000712/