Archive for September, 2014

Is Sitting At Your Desk Killing You?

Tuesday, September 30th, 2014

My public notes from the Yale Day of Data (#ydod2014, i0dataday)

Tuesday, September 30th, 2014

The Institute for Data Intensive Engineering and Science – The Data-Scope

Tuesday, September 30th, 2014

Coppi mentions: JHU’s Data-scope ( ), which has a specialized architecture for astronomical computation #ydod2014

4 PB / yr

What Big Data means to me — Bourne 21 (2): 194 — Journal of the American Medical Informatics Association

Tuesday, September 30th, 2014

Bourne mentions “What Big Data means to me”
( ) in connection with the creation of a digital ecosystem #ydod2014

Analysis of noncoding regulatory mutations in cancer

Monday, September 29th, 2014

An interesting report of potential non-coding drivers without actually doing any wet lab work.

“These methods identify recurrent mutations in regulatory elements upstream of PLEKHS1, WDR74 and SDHD, as well as previously identified mutations in the TERT promoter”. In the text they mention “Khurana et al. also reported WDR74 promoter mutations in 2 of the 20 prostate cancer genomes analyzed”.

Bina QC Report for Single Sample

Monday, September 29th, 2014

Nice viz of the quality of a single sequencing run
{Disclaimer I’m a consultant to this company.}

PLOS Computational Biology: Spatial Generalization in Operant Learning: Lessons from Professional Basketball

Monday, September 29th, 2014

Spatial Generalization in… Learning: Lessons from… #Basketball How past success changes your tendencies to shoot

Describes constructing a learning matrix for how a player will update his tendency to shoot
from a certain region of the court based on his past successes or failures

The Parable of Google Flu: Traps in Big Data Analysis

Monday, September 29th, 2014

Parable of #Google Flu: Traps in #BigData Analysis Replicating results is hard, w/ an ever-changing search algorithm


For Big-Data Scientists, ‘Janitor Work’ Is Key Hurdle to Insights

Monday, September 29th, 2014

For #BigData Scientists, Janitor Work Is Key Is a #datascientist a digital maid or a data priest? Perhaps a hybrid.

O’Neil talk

Blood transciptome paper

Sunday, September 28th, 2014

Splicing changes along the blood lineage, good ex. of the
state-of-the-art in human transcriptomics

Science 26 September 2014:
Vol. 345 no. 6204
DOI: 10.1126/science.1251033

Transcriptional diversity during lineage commitment of human blood progenitors

Chen et al.