Archive for December, 2015

21khz: The Art of Money In Music

Thursday, December 31st, 2015

Some quick thoughts after listening to first 9 episodes

“Will Musicians Survive in the Age of Free When the “Bottle” is worth more than the wine” – a great line & an observation that the spotify platform is worth more than its music . See also:

“Intent, Licenses and “Sweat of the Brow” – helpful discussion of copyright but it would have been nice to hear about copyleft & re-combining of artworks

“two letters and a number” – was originally someone’s name. Robertson’s story how on how to be sued & wooed simultaneously

“so… Why does Liza Minnelli get paid when the Sex Pistols Stream?” – how to weight things (downloads or listeners) & various frauds based on this…

Can you Sell Something that Doesn’t Exist? – Superfans: would you rather collect unemployment or by the latest Doors album?

Mind Mapping Software: Mind Maps | MindMeister

Thursday, December 31st, 2015

perhaps useful for workflow viz

About Us |

Thursday, December 31st, 2015

Spire – Wearable activity and respiration tracking for a healthy body and mind.

Wednesday, December 30th, 2015

Interesting …..

A Field Guide to Psychedelics – The New Yorker

Wednesday, December 30th, 2015

For the Wealthiest, a Private Tax System That Saves Them Billions –

Wednesday, December 30th, 2015

Posture Affects Standing, and Not Just the Physical Kind –

Wednesday, December 30th, 2015

15 Essential Chrome Extensions For Google Drive

Tuesday, December 29th, 2015

It’s Time to End the War on Salt – Scientific American

Monday, December 28th, 2015

Ewing AD*, Houlahan KE…..Stuart JM, Boutros PC (2015) “Combining accurate tumour genome simulation with crow d-sourcing to benchmark somatic single nucleotide variant detection” Nature Methods 12(7):623-630 (PMID: 25984700)

Monday, December 28th, 2015

Tumor genome simulation w/ #crowdsourcing to benchmark…SNV detection Addresses lack of gold standards & privacy

Ewing, Houlahan…..Stuart, Boutros (2015) “Combining accurate
tumour genome simulation with crowd-sourcing to benchmark somatic
single nucleotide variant detection” Nature Methods 12(7):623-630
(PMID: 25984700)

A crowdsourced benchmark of somatic mutation detection algorithms was
introduced for the ICGC-TCGA DREAM challenge. This has the advantage
of dealing with the lack of gold standard data and the issue of
sharing private genomic data. All groups worked on three different
simulated tumor-normal pairs generated with BAMSurgeon, by directly
adding synthetic mutations to existing reads. An ensemble of
pipelines outperforms the best individual pipeline in all cases,
assessed on the basis of recall, precision and F-score.
Parameterization and genomic localization both have an effect on
pipeline performance, while characteristics of prediction errors
differed for most pipelines.