Posts Tagged ‘entex’

GWAS ATLAS resource

Saturday, August 24th, 2019

A global overview of pleiotropy and genetic architecture in complex traits

Kyoko Watanabe, Sven Stringer, Oleksandr Frei, Maša Umićević Mirkov, Christiaan de Leeuw, Tinca J. C. Polderman, Sophie van der Sluis, Ole A. Andreassen, Benjamin M. Neale & Danielle Posthuma

https://www.nature.com/articles/s41588-019-0481-0

Genome-wide analysis of polymerase III-transcribed Alu elements suggests cell-type-specific enhancer function.

Sunday, August 18th, 2019

https://genome.cshlp.org/content/early/2019/08/14/gr.249789.119.long

Single Cell Resource for Mouse

Saturday, August 3rd, 2019

QT:{{”

Tabula Muris is a compendium of single cell transcriptome data from the model organism Mus musculus, containing nearly 100,000 cells from 20 organs and tissues. The data allow for direct and controlled comparison of gene expression in cell types shared between tissues, such as immune cells from distinct anatomical locations. They also allow for a comparison of two distinct technical approaches: “}}

https://tabula-muris.ds.czbiohub.org/

Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits | bioRxiv

Thursday, July 12th, 2018

https://www.biorxiv.org/content/early/2017/10/15/203380

Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits

Farhad Hormozdiari, Steven Gazal, Bryce van de Geijn, Hilary Finucane, Chelsea J.-T. Ju, Po-Ru Loh, Armin Schoech, Yakir Reshef, Xuanyao Liu, Luke O’Connor, Alexander Gusev, Eleazar Eskin, Alkes Price
doi: https://doi.org/10.1101/203380

differential Hi-C analysis

Wednesday, July 11th, 2018

https://genome.cshlp.org/content/28/3/412.long

It is kind of a similar idea about finding the differential chromatin interactions

mammalian tissue expression database

Saturday, June 2nd, 2018

curated tissue expression database for mammalians: human, mouse, rat, pig

web: https://tissues.jensenlab.org/
paper: https://academic.oup.com/database/article/doi/10.1093/database/bay003/4851151 a relevant figure:
https://academic.oup.com/view-large/figure/112879298/bay003f2.tif

illumina platinum genomes paper

Tuesday, January 10th, 2017

Set of 5.4M phased…variants…from seq. a 3-gen. 17-member [CEPH] pedigree, centered on #NA12878
http://genome.cshlp.org/content/early/2016/11/25/gr.210500.116 $ILMN Pt genomes

A reference data set of 5.4 million phased human
variants validated by genetic inheritance from
sequencing a three-generation 17-member pedigree

Michael A. Eberle,1 Epameinondas Fritzilas,2 Peter Krusche,2 Morten Källberg,2 Benjamin L. Moore,2 Mitchell A. Bekritsky,2 Zamin Iqbal,3 Han-Yu Chuang,1 Sean J. Humphray,2 Aaron L. Halpern,1 Semyon Kruglyak,1 Elliott H. Margulies,1 Gil McVean,3,4 and David R. Bentley2

http://genome.cshlp.org/content/early/2016/11/25/gr.210500.116

Scientists are assembling a new picture of humanity

Sunday, December 4th, 2016

Assembling a new picture of humanity by @CarlZimmer
https://www.statnews.com/2016/10/07/dna-genome-sequencing-new-maps/ 1 graph to represent everyone, counterpoint to #personalgenomes

Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals. – PubMed – NCBI

Sunday, August 7th, 2016

Allele-specific TF binding in liver & cervix cells [HepG2 & HeLa] unveils many likely drivers of GWAS [SNP] signals
http://www.sciencedirect.com/science/article/pii/S0888754316300271