linkstream2 microblog

https://www.wired.com/story/biology-will-be-the-next-great-computing-platform/

Here is the link to the new 150 deeply Illumina- sequenced 1000 Genomes samples…

https://www.ebi.ac.uk/ena/data/view/PRJEB20654
https://github.com/Illumina/Polaris/wiki/HiSeqX-Diversity-Panel

There is also a planned trio panel (51 trios) and a repeat expansion project.

https://github.com/Illumina/Polaris/

a link to details on IvyPlus exchange program:
https://gsas.yale.edu/academics/exchanges/exchange-scholar-program-ivyplus-exchange

turns out Imperial College London is the institution that left U of London. UCL is still part of U of London
indeed: https://www.theguardian.com/education/2005/dec/09/highereducation.administration

Interesting paper by alumnus Renqiang Min on “Video Generation from Text,” using a generative #MachineLearning model.
http://www.AAAI.org/GuideBook2018/16152-72279-GB.pdf (Press report by @SilverJacket: New algorithm can create movies from just a few snippets of text
http://www.ScienceMag.org/news/2018/02/new-algorithm-can-create-movies-just-few-snippets-text )

Video Generation from Text Yitong Li†∗, Martin Renqiang Min‡ , Dinghan Shen† , David Carlson† , Lawrence Carin† †

https://www.nature.com/articles/nature25980

A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

Suijuan Zhong
, Shu Zhang
[…]
Xiaoqun Wang
Nature
doi:10.1038/nature25980

http://www.in.emb-japan.go.jp/PDF/(15)Some%20of%20the%20Publications%20by%20H.M.Emperor%20Akihito.pdf Some of the Publications by His Majesty Emperor Akihito
www.in.emb-japan.go.jp
Some of the Publications by His Majesty Emperor Akihito The Emperor, then Crown Prince Akihito, co-authored the entry on gobiid fishes in the The Fishes of the

Received: 13 November 2017 Revised: 22 November 2017 Accepted: 29 November 2017 https://www.nature.com/articles/s41525-017-0040-5.pdf

Common #schizophrenia alleles are enriched in mutation-intolerant genes & in regions under strong background selection
https://www.nature.com/articles/s41588-018-0059-2 50 novel SCZ loci & 145 loci in total, from #GWAS – associated w/ 33 candidate causal genes

QT:{{”
We report a new genome-wide association study of schizophrenia (11,260 cases and 24,542 controls), and through meta-analysis with existing data we identify 50 novel associated loci and 145 loci in total. Through integrating genomic fine-mapping with brain expression and chromosome conformation data, we identify candidate causal genes within 33 loci.
“}}

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nature Genetics (2018)
doi:10.1038/s41588-018-0059-2

Glowing Auras & Black Money: The Pentagon’s Mysterious #UFO Program
https://www.nytimes.com/2017/12/16/us/politics/pentagon-program-ufo-harry-reid.html Rather incredible that this exists. I’m sure it’ll spawn many movies…

Dynamic Topic Models
https://mimno.infosci.cornell.edu/info6150/readings/dynamic_topic_models.pdf Classic work by @Blei_lab & J Lafferty adapts the #LDA formalism describing documents in terms of latent topics – to allow these to evolve over time