Posts Tagged ‘quote’

Cc2d2a Chemically induced Allele Detail MGI Mouse (MGI:5311382)

Monday, August 19th, 2019

http://www.informatics.jax.org/allele/MGI:5311382

b2b1035Clo = Blue meanie mutation

QT:{{”
Cc2d2ab2 ^ b1035Clo
Name:coiled-coil and C2 domain containing 2A; Bench to Bassinet Program (B2B/CVDC), mutation 1035 Cecilia Lo
MGI ID:MGI:5311382
Synonyms:Blue meanie
Gene:Cc2d2a Location: Chr5:43662373-43740975 bp, + strand Genetic Position: Chr5, 23.78 cM
Heterotaxy indicated by left lung isomerism with left sided IVC and TGA (observed by EFIC imaging)


Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a C to T substitution at coding nucleotide 2845 in exon 23 of the cDNA (c.2845C>T, NM_172274). This changes the arginine residue to a translation stop at position 949 of the encoded protein (p.R949*). (J:175213) Additional incidental mutations were detected in sequencing for the causative mutation, Cc2d2ab2b1035Clo, and may be present in stocks carrying this mutation.
“}}

Desperately seeking scientists | Nature Index

Monday, August 12th, 2019

Reunion coverage + Useful suggestion for ORCID that can be done with a secondary email

https://www.natureindex.com/news-blog/one-in-five-email-addresses-researcher-journal-articles-invalid-problem

QT:{{”
Mark Gerstein, the Albert Williams Professor of Biomedical Informatics at Yale University in New Haven, Connecticut, lists over 200 members on his lab’s alumni page, about half of whom were PhD students and postdocs. Recently, he invited many of them to a lab reunion. But first, he had to find them.
“It’s a nontrivial thing keeping track of peoples’ emails,” he says. The lab maintains a database of past members, but he’s now established a LinkedIn group, which has been particularly useful, he says. Former lab members who are on the social network can associate themselves with the lab, thus providing a mechanism for staying in touch. If nothing else, Gerstein notes, he likes to be able to contact lab expats in case there’s ever a question about an old project – for instance, to clarify a protocol or locate a file.

A third solution would be for a third-party ‘scientific directory’ service such as ORCID to add a mechanism for contacting authors, such as a button or form to send a message.
Laure Haak, Executive Director of ORCID, says, “At the current time, ORCID does not have these features on our roadmap.”
In the meantime, it is possible to make the email addresses in an ORCID profile public; go to Account Settings > Email and Notification Preferences, and change “who can see this” from “only me” to “everyone”.
Of course, even were the organization to add a messaging feature, overtaxed researchers may not read them.
“People get so much email,” Gerstein says. “I suspect people would ignore the messages.”
“}}

The Books of College Libraries Are Turning Into Wallpaper

Sunday, August 11th, 2019

QT:{{”
“But there is another future that these statistics and our nostalgic reaction to them might produce: the research library as a Disneyland of books, with banker’s lamps and never-cracked spines providing the suggestion of, but not the true interaction with, knowledge old and new. As beautiful as those libraries appear—and I, too, find myself unconsciously responding to such surroundings, having grown up studying in them—we should beware the peril of books as glorified wallpaper. The value of books, after all, is what lies beneath their covers, as lovely as those covers may be.
“}}

https://www.theatlantic.com/ideas/archive/2019/05/college-students-arent-checking-out-books/590305/

Low-level password protection

Sunday, August 4th, 2019

QT:{{”
You set up two pages (e.g., page.html and protectpage.html). page.html has the javascript code snippet within the tags. protectpage.html has the protected information. If someone enters the correct password — ‘letmein’ in the example — the protected page opens in a new browser window.

Of course, the password is identifiable by viewing page source. Also, a webcrawling bot will probably index or scrape protectpage.html at some point.

Anything more sophisticated is challenging.
“}}

http://www.javascriptkit.com/script/cut10.shtml

Low-level password protection

Sunday, August 4th, 2019

QT:{{”
You set up two pages (e.g., page.html and protectpage.html). page.html has the javascript code snippet within the tags. protectpage.html has the protected information. If someone enters the correct password — ‘letmein’ in the example — the protected page opens in a new browser window.

Of course, the password is identifiable by viewing page source. Also, a webcrawling bot will probably index or scrape protectpage.html at some point.

Anything more sophisticated is challenging.
“}}

Theranos Whistleblower Shook the Company—and His Family – WSJ

Sunday, August 4th, 2019

https://www.wsj.com/articles/theranos-whistleblower-shook-the-companyand-his-family-1479335963
QT:{{”
Tyler Shultz says he wanted to shield reputation of former Secretary of State George Shultz, a Theranos director and his grandfather; $400,000 in legal fees
“}}

A Decade Ago, a Scientist Promised a Brain Simulation in a Decade

Saturday, August 3rd, 2019

QT:{{”
“In a recent paper titled “The Scientific Case for Brain Simulations,” several HBP scientists argue that big simulations “will likely be indispensable for bridging the scales between the neuron and system levels in the brain.” In other words: Scientists can look at the nuts and bolts of how neurons work, and they can study the behavior of entire organisms, but they need simulations to show how the former creates the latter. The paper’s authors draw a comparison to weather forecasts, in which an understanding of physics and chemistry at the scale of neighborhoods allows us to accurately predict temperature, rainfall, and wind across the whole globe.”
“}}

https://www.theatlantic.com/science/archive/2019/07/ten-years-human-brain-project-simulation-markram-ted-talk/594493/

Bluetooth was named after a Danish King (but just bad tooth?)

Saturday, August 3rd, 2019

https://en.wikipedia.org/wiki/Harald_Bluetooth

“The first documented appearance of Harald’s nickname “Bluetooth” (as blatan; Old Norse *blátǫnn) is in the Chronicon Roskildense (written ca. 1140), alongside the alternative nickname Clac Harald.[5] Clac Harald appears to be a confusion of Harald Bluetooth with the legendary or semi-legendary Harald Klak, son of Halfdan. The byname is given as Blachtent and explicitly glossed as “bluish or black tooth” (dens lividus vel niger) in a chronicle of the late 12th century, Wilhelmi abbatis regum Danorum genealogia.[6] The traditional explanation is that Harald must have had a conspicuous bad tooth that appeared “blue” (i.e. “black”, as blár “blue” meant “blue-black”, or “dark-coloured”). Another explanation, proposed by Scocozza (1997) is that he was called “blue thane” (or “dark thane”) in England (with Anglo-Saxon thegn corrupted to tan when the name came back into Old Norse).[7]”

His dark materials | 1843

Monday, July 22nd, 2019

https://www.1843magazine.com/design/his-dark-materials

QT:{{”
The material he’s describing is Vantablack – the blackest black ever created. It was developed by a company called Surrey NanoSystems (SNS), whose laboratory is housed in a single-storey, pre-fab block in a dreary business park near the port at Newhaven, on Britain’s south coast. Vantablack is made from carbon nanotubes (“Vanta” stands for “vertically aligned nanotube array”). Each tube is just a few nanometres thick and a few hundred nanometres tall – that is, just a few billionths of a metre.
“}}

Unpacking the innards of Theranos’s new Zika-detection box | TechCrunch

Sunday, June 9th, 2019

https://techcrunch.com/2016/08/05/unpacking-theranoss-magic-zika-detection-box/ QT:{{”
So it was in this dark night of despair that Holmes told members of the media and the science community she would finally be opening up about Edison, her one-drop blood analysis technology 11 years in the making. Hundreds of scientists lined up at the American Association for Clinical Chemistry this week in the hopes of finally getting a behind-the-scenes look at the secret machine. Instead, they got an introduction to an entirely new product — an all-in-one Zika-detecting tabletop miniLab.
“}}