linkstream2 microblog

http://www.sciencedirect.com/science/article/pii/S1074552197903215

http://www.cell.com/ajhg/abstract/S0002-9297(14)00055-X

http://www.annualreviews.org/doi/abs/10.1146/annurev-genom-090413-025448

QT:{{”
“Exploration has a second meaning: Running pilot tests to explore ideas, refine procedures and tasks, and guide where precious research effort is best directed is often one of the most rewarding stages of research. No matter how intriguing, however, the results of such pilot work rarely deserve even a brief mention in a report. The aim of such work is to discover how to prespecify in detail a study that is likely to find answers to our research questions, and that must be reported. Any researcher needs to choose the moment to switch from
not-for-reporting pilot testing to prespecified, must-be-reported research.”
“}}

http://pss.sagepub.com/content/early/2013/11/07/0956797613504966.long

The fine-scale genetic structure of the British population
http://www.nature.com/nature/journal/v519/n7543/full/nature14230.html Correlation w. geography, reflecting Anglo-Saxon migration

http://www.nature.com/nature/journal/v519/n7543/full/nature14230.html

Cost of #Reproducibility http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002165 Estimated at almost $30B for life science research, based on 50% of studies not replicating

#Transcriptome analysis [focusing on brain tissue]
using…long-read[s]…reveals…co-association of
distant…exonshttp://www.nature.com/nbt/journal/vaop/ncurrent/abs/nbt.3242.html

Mostly protein coding genes

http://www.pnas.org/content/111/27/9869.full

http://www.nature.com/nbt/journal/v33/n6/abs/nbt.3238.html

http://www.cell.com/cell/abstract/S0092-8674(11)01062-2?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867411010622%3Fshowall%3Dtrue