Archive for the ‘SciLit’ Category

PLOS Computational Biology: PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations

Monday, November 28th, 2016

PredictSNP…Consensus Classifier for Prediction of Disease-Related
Mutations http://journals.PLOS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003440 Demo of various #ensemble approaches

De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets | BMC Genomics | Full Text

Friday, November 25th, 2016

De novo prediction of cis-regulatory…modules through integrative analysis of a large number of ChIP datasets
http://BMCGenomics.BiomedCentral.com/articles/10.1186/1471-2164-15-1047 [1/2]
Only calls modules w/ overrepresented pairs of TFBSes – based on observation that well-known promotors have extensive co-regulation [2/2]

De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets

Meng Niu,
Ehsan S Tabari and
Zhengchang Su

Health Care Infrastructure for Financially Sustainable Clinical Genomics

Tuesday, November 15th, 2016

http://jmd.amjpathol.org/article/S1525-1578(16)30086-1/pdf
billing figure

miRNA atlas

Tuesday, November 1st, 2016

Distribution of #miRNA expression across human tissues
http://nar.oxfordjournals.org/content/44/8/3865 Atlas of ~1400 RNAs in at least 1 of 61 tissues; 143 in all

https://ccb-web.cs.uni-saarland.de/tissueatlas/

Frustration in biomolecules | Quarterly Reviews of Biophysics | Cambridge Core

Tuesday, November 1st, 2016

#Frustration in biomolecules
https://www.cambridge.org/core/journals/quarterly-reviews-of-biophysics/article/frustration-in-biomolecules/DECEA176849986FC11DB079C1EB4B24A Reviews the field: how large molecules pay a local price to achieve global stability

Succinct de Bruijn Graphs – Springer

Sunday, October 30th, 2016

http://link.springer.com/chapter/10.1007/978-3-642-33122-0_18

Uncovering Earth’s virome : Nature : Nature Research

Friday, October 21st, 2016

Uncovering Earth’s virome
http://www.nature.com/nature/journal/v536/n7617/full/nature19094.html Meta analysis of 5Tb of extant #metagenomic sequences finds >125k partial viral genomes

David Paez-Espino, Emiley A. Eloe-Fadrosh, Georgios A. Pavlopoulos, Alex D. Thomas, Marcel Huntemann, Natalia Mikhailova, Edward Rubin, Natalia N. Ivanova & Nikos C. Kyrpides

Looking for a Signal in the Noise: Revisiting Obesity and the Microbiome

Sunday, October 16th, 2016

QT:{{"
Katherine Pollard led one study, and Rob Knight led the other
(Finucane et al., 2014; Walters et al., 2014).
"}}

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999546/

Genome expansion via lineage splitting and genome reduction in the cicada endosymbiont Hodgkinia

Sunday, October 16th, 2016

http://www.pnas.org/content/112/33/10192.abstract

PLOS Computational Biology: PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions

Sunday, October 9th, 2016

PredictSNP2: A Unified Platform http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004962 Ensembles many scores for the impact of non-coding variants, including #FunSeq