Archive for April, 2014

How to Get a Job at Google – NYTimes.com

Sunday, April 6th, 2014

How to Get a Job at #Google: know how to learn, when to lead & when to follow. Useful for hiring students & postdocs!
http://www.nytimes.com/2014/02/23/opinion/sunday/friedman-how-to-get-a-job-at-google.html

The Transcription Factor Titration Effect Dictates Level of Gene Expression

Sunday, April 6th, 2014

Interesting study looking at the effect of gene duplication on TF binding
"…when a TF is shared among many binding sites, either due to multiple identical copies of a gene regulated by that TF or due to unrelated genes that also independently bind the TF, the correlation in occupancy between the binding sites will lead to a complex dosage response to that TF." http://www.cell.com/abstract/S0092-8674(14)00221-9

Park Lane Hotel | NYC Restaurants | NYC Bars

Sunday, April 6th, 2014

11a-1230a
no table cloths – might be suitable for a read!
http://www.parklanenewyork.com/restaurants-bars

Genome-wide signals of positive selection in human evolution

Sunday, April 6th, 2014

http://genome.cshlp.org/content/early/2014/03/11/gr.164822.113.abstract

“We further demonstrate that the observed signatures of positive selection correlate better with the presence of regulatory sequences, as predicted by the ENCODE Project Consortium, than with the positions of amino acid substitutions. Our results suggest that adaptation was frequent in human evolution and provide support for the hypothesis of King and Wilson that adaptive divergence is primarily driven by regulatory changes.”

Similar to conclusion positive-section section in FunSeq paper

Finding the lost treasures in exome sequencing data

Sunday, April 6th, 2014

Finding lost treasures in #exome sequencing data. Mining off-target, often noncoding, reads from 1000G, TCGA, ESP, &c
http://www.ncbi.nlm.nih.gov/pubmed/23972387

NYT Now: Amazon Fire TV Review: The Set-Top Box Just Evolved – WSJ.com

Sunday, April 6th, 2014

http://blogs.wsj.com/personal-technology/2014/04/04/amazon-fire-tv-review-the-set-top-box-just-evolved/

FYI: The Cofounder Of 23andMe’s Next Project: Mining Your Quantified Self

Sunday, April 6th, 2014

Cofounder Of 23andMe’s Next Project: Mining Your #QuantifiedSelf. @lindaavey’s @WeAreCurious creates a forum for this
http://www.fastcoexist.com/3027630/the-cofounder-of-23andmes-next-project-mining-your-quantified-self

Artist Incorporates Emoji Into Famous Artworks PHOTOS

Sunday, April 6th, 2014

Would #Hopper approve? MT @mashable: artist remixed famous artworks by incorporating #emoji: http://t.co/XXDloPJF3m http://t.co/uu9OPk04Au

http://mashable.com/2014/04/05/classic-art-emoji-culture

paper on cancer driver genes in RECOMB 2014

Sunday, April 6th, 2014

paper from RECOMB 2014 might be interesting to you, which uses
hitting time in random walk to identify cancer drivers.

http://link.springer.com/chapter/10.1007%2F978-3-319-05269-4_23

HIT.nDRIVE: Multi-Driver Gene Prioritization based on Hitting Time

Raunak Shrestha, Ermin Hodzic, Jake Yeung, Kendric Wang, Thomas
Sauerwald, Phuong Dao, Shawn Anderson, Himisha Beltran, Mark A. Rubin,
Colin Collins, Gholamreza Haffari and S. Cenk Sahinalp.

eggs

Sunday, April 6th, 2014

http://www.smithsonianmag.com/smart-news/digitally-hunt-easter-eggs-new-york-city-180950346