Posts Tagged ‘regnet’

The Transcription Factor Titration Effect Dictates Level of Gene Expression

Sunday, April 6th, 2014

Interesting study looking at the effect of gene duplication on TF binding
"…when a TF is shared among many binding sites, either due to multiple identical copies of a gene regulated by that TF or due to unrelated genes that also independently bind the TF, the correlation in occupancy between the binding sites will lead to a complex dosage response to that TF."