Cell Signaling by Receptor Tyrosine Kinases: Cell
Saturday, May 20th, 2017[category scilit]
Cell signaling by #RTKs Nice 1st fig showing 20 sub-families and architecture of extra- & intra- cellular domains
Posts Tagged ‘from_talk’
Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution: Cell
Sunday, February 5th, 2017Temporal Collateral Sensitivity in Tumor…Evolution
http://www.cell.com/cell/abstract/S0092-8674(16)30059-9 Drug-fitness landscape illuminates transiently vulnerable state
Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution
Boyang Zhao
Joseph C. Sedlak
Raja Srinivas
Pau Creixell
Justin R. Pritchard
Bruce Tidor
Douglas A. Lauffenburger
Michael T. Hemann
PicnicHealth | Medical Records Done for You
Saturday, December 31st, 2016computerizes your med. records
PicnicHealth | Medical Records Done for You
Sunday, December 11th, 2016Identification of type 2 diabetes subgroups through topological analysis of patient similarity | Science Translational Medicine
Saturday, July 16th, 2016Patient records
Http://stm.sciencemag.org/content/7/311/311ra174
Magical gadget scans your food to reveal its nutritional value
Friday, May 6th, 2016MicroRNA silencing for cancer therapy targeted to the tumour microenvironment : Nature : Nature Publishing Group
Friday, April 8th, 2016miRNA silencing for…therapy targeted to the [acidic] tumor microenviron., w/ #pHLIP
http://www.nature.com/nature/journal/v518/n7537/abs/nature13905.html miR-155 moves beyond biomarker
DREM 2.0: Improved reconstruction of dynamic regulatory networks from time-series expression data | BMC Systems Biology | Full Text
Friday, April 8th, 2016DREM…reconstruction of…regulatory #networks from time-series expression http://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-6-104 Classic approach using 3-level IO #HMMs
Visualizing virus assembly intermediates inside marine cyanobacteria : Nature : Nature Publishing Group
Tuesday, June 16th, 2015Visualizing virus assembly…inside…bacteria
http://www.nature.com/nature/journal/v502/n7473/full/nature12604.html Phase-contrast #cryoET resolves subcellular structures (eg ribosomes)
Cryo-ET determines diff structural snapshots virus during assembly. One tomogram to work out whole pathway.
Wei Dai,
Caroline Fu,
Desislava Raytcheva,
John Flanagan,
Htet A. Khant,
Xiangan Liu,
Ryan H. Rochat,
Cameron Haase-Pettingell,
Jacqueline Piret,
Steve J. Ludtke,
Kuniaki Nagayama,
Michael F. Schmid,
Jonathan A. King
& Wah Chiu
Nature 502, 707–710 (31 October 2013) doi:10.1038/nature12604
Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL
Friday, March 27th, 2015RUNX1 is most connected in TLX1 & 3 expr. net. It’s a tumor suppressor disabled by LOF mutations.
Rev. engineering…identifies RUNX1 as tumor suppressor in T-ALL http://www.nature.com/nm/journal/v18/n3/full/nm.2610.html It’s the most connected TF in the expression network
Nat Med. Author manuscript; available in PMC 2012 Sep 1.
Nat Med. 2012 Feb 26; 18(3): 436–440.
Published online 2012 Feb 26. doi: 10.1038/nm.2610
Giusy Della Gatta,1 Teresa Palomero,1,2 Arianne Perez-Garcia,1 Alberto Ambesi-Impiombato,1 Mukesh Bansal,3Zachary W. Carpenter,1 Kim De Keersmaecker,4,5 Xavier Sole,6,7 Luyao Xu,1 Elisabeth Paietta,8,9 Janis Racevskis,8,9Peter H Wiernik,8,9 Jacob M Rowe,10 Jules P Meijerink,11 Andrea Califano,1,3 and Adolfo A. Ferrando1,2,12