Posts Tagged ‘chromatin’

Spatial confinement is a major determinant of the folding landscape of human chromosomes

Thursday, July 28th, 2016

Gamze Gursoy, Yun Xu, Amy Kenter and Jie Liang. “Spatial confinement is a major determinant of folding landscape of human genome”, Nucleic Acids Research, 2014, 42 (13), 8223-8230

Confinement is a major determinant of the #folding…of chromosomes http://NAR.oxfordjournals.org/content/42/13/8223.full Simulations of self-avoiding chain growth

http://nar.oxfordjournals.org/content/42/13/8223.full

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CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription: Cell

Friday, March 4th, 2016

CTCF-Mediated…3D Genome Architecture
http://www.cell.com/cell/abstract/S0092-8674(15)01504-4 SNPs give different #chromatin topologies, including strong #allelic effects

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Cell-of-origin chromatin organization shapes the mutational landscape of cancer : Nature : Nature Publishing Group

Wednesday, September 2nd, 2015

#Chromatin…shapes the mutational landscape of cancer
http://www.nature.com/nature/journal/v518/n7539/full/nature14221.html Low DNase correlates w/ high SNVs in melanoma. True generally?

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cancer mutation rates versus chromatin

Saturday, June 14th, 2014

Chromatin organization is a major influence on regional mutation rates in human cancer cells
Benjamin Schuster-Böckler & Ben Lehner

http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature11273.html

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Science Focus on Gary Felsenfeld: untangling chromatin’s mysteries

Tuesday, September 4th, 2012

http://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=13067

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