Is this tetrahedral?
Ir-containing compound w/ a formal #oxidation state of IX http://www.nature.com/nature/journal/v514/n7523/full/nature13795.html
Surpassing OsO4, removing d electron gives [IrO4]+ cation
"Removal of the remaining d electron from IrO4 would lead to the iridium tetroxide cation ([IrO4]+)"
Genotype to phenotype relationships in ASD http://www.nature.com/neuro/journal/v18/n2/abs/nn.3907.html Expression differences in #brain development for LOF-containing, M v F, &c
Also, netbag finds subnets assoc w autism
Human & mouse [mRNA] #methylomes revealed by m6A-seq http://www.nature.com/nature/journal/v485/n7397/full/nature11112.html Conservation across species & conditions (for most sites)
Dan Dominissini,
Sharon Moshitch-Moshkovitz,
Schraga Schwartz,
…
Rotem Sorek
& Gideon Rechavi
Nature 485, 201–206 (10 May 2012) doi:10.1038/nature11112
Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators http://www.nature.com/nature/journal/v508/n7497/full/nature13206.html Reconstructed #evolution across 8 species
Daniel W. Bellott,
Jennifer F. Hughes,
…
Richard A. Gibbs,
Richard K. Wilson
& David C. Page
Nature 508, 494–499 (24 April 2014) doi:10.1038/nature13206
Spacetime wiring specificity supports…selectivity in the retina http://www.nature.com/nature/journal/v509/n7500/full/nature13240.html @eye_wire citizenscience traces neural connectivity
finds a time lag circuit
Jinseop S. Kim,
Matthew J. Greene,
…
H. Sebastian Seung
& the EyeWirers
Nature 509, 331–336 (15 May 2014) doi:10.1038/nature13240
High-res mapping reveals a conserved…mRNA methylation program http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956118/ Predicting methyl sites w/ seq., structure & position
Cell. 2013 Dec 5; 155(6): 1409–1421.
Published online 2013 Nov 21. doi: 10.1016/j.cell.2013.10.047 PMCID: PMC3956118
NIHMSID: NIHMS550466
High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program
Schraga Schwartz,1,* Sudeep D. Agarwala,2,* Maxwell R. Mumbach,1 Marko Jovanovic,1 Philipp Mertins,1 Alexander Shishkin,1 Yuval Tabach,3,4 Tarjei S Mikkelsen,1 Rahul Satija,1 Gary Ruvkun,3,4 Steven A. Carr,1 Eric S. Lander,1,5,6 Gerald R. Fink,1,2,8 and Aviv Regev 1,7,8
Privacy in Pharmacogenetics…Personalized Warfarin Dosing
https://www.usenix.org/conference/usenixsecurity14/technical-sessions/presentation/fredrikson_matthew Model-inversion attack; differential privacy doesn’t help
Authors:
Matthew Fredrikson, Eric Lantz, and Somesh Jha, University of Wisconsin—Madison; Simon Lin, Marshfield Clinic Research Foundation; David Page and Thomas Ristenpart, University of Wisconsin—Madison
Awarded Best Paper!
Analysis of high-throughput B-cell sequencing
http://www.pnas.org/content/early/2015/02/05/1417683112.abstract Successful locus-level application of #personalgenome construction
WGBS…reveals complementary roles of promoter & gene-body
#methylation in…regulation http://genomebiology.com/content/15/7/408 Has model for gene expression
Hysteresis in a quantized #superfluid atomtronic circuit
http://www.nature.com/nature/journal/v506/n7487/full/nature12958.html Moving atoms instead of electrons for future storage devices
Stephen Eckel,
Jeffrey G. Lee,
Fred Jendrzejewski,
Noel Murray,
Charles W. Clark,
Christopher J. Lobb,
William D. Phillips,
Mark Edwards
& Gretchen K. Campbell
Nature 506, 200–203 (13 February 2014) doi:10.1038/nature12958
QT:{{”
Atomtronics1, 2 is an emerging interdisciplinary field that seeks to develop new functional methods by creating devices and circuits where ultracold atoms, often superfluids, have a role analogous to that of electrons in electronics. Hysteresis is widely used in electronic circuits—it is routinely observed in superconducting circuits3 and is essential in radio-frequency superconducting quantum interference devices4. Furthermore, it is as fundamental to superfluidity5 …. “}}