Archive for May, 2016
Released Emails Show Use of Unclassified Systems Was Routine – The New York Times
Wednesday, May 11th, 2016The Independent Discovery of TCP/IP, By Ants
Tuesday, May 10th, 2016Genetic Analysis of 250 Burgers Reveals Some Unsavory Surprises
Tuesday, May 10th, 2016Helix conducts research as you write | TechCrunch
Monday, May 9th, 2016Ambient Furniture from MIT- Postscapes
Sunday, May 8th, 2016Has skype cabinet
http://postscapes.com/ambient-furniture-from-mit
Can Gizmos Cure Insomnia? – The New Yorker
Sunday, May 8th, 2016In search of 40 winks
http://www.newyorker.com/magazine/2016/02/08/in-search-of-forty-winks Nice but slightly critical survey of #sleep gadgets (trackers, beds, snore suppressors, &c)
Why Aren’t There More Scientists? A One-Word Explanation
Sunday, May 8th, 2016Q: Why Aren’t There More Scientists? A: Money
http://phenomena.nationalgeographic.com/2016/04/29/why-we-dont-produce-more-scientists-a-one-word-explanation/ Breakdown of how a field’s $6M in NSF #funding is apportioned HT @gnat
QT:{{”
“Every year Congress gives the National Science Foundation roughly 7.3 billion dollars. That sum hasn’t changed much (in real terms) for decades. The Defense Department gets $573 billion. But $7.3 billion isn’t bad. “It sounds like a lot of money,” says Jahren, even if it’s spread across biology, geology, chemistry, mathematics, physics, psychology, sociology, and some computer science.
Divided 50 times—assuming one paleobiologist in every state—that works out to $120,000 per grant. In fact, Jahren counted between 30 and 40 grants per year, for an average of $165,000. Assuming some of those scientists hire assistants, she figures there are “about 100 [government] funded paleobiologists in America.””
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History as Seen on Mad Men: A Timeline | TIME
Sunday, May 8th, 2016Cell lineage analysis in human brain using endogenous retroelements. – PubMed – NCBI
Saturday, May 7th, 2016Cell-lineage analysis in human #brain using endogenous retroelements http://www.cell.com/neuron/abstract/S0896-6273(14)01137-4 Tracing L1 insertions w/ #singlecell sequencing
Using single cell WGS of 16 neuronal cells the authors investigated two somatic insertions of L1Hs elements in an adult human brain. Using these results the authors infer that L1 somatic insertions are infrequent and ALUs and SVAs somatic retrotransposition are extremely rare. Assessing two L1Hs insertions in 32 samples across different regions of this same adult brain, they found that while one insertion was spatially restricted (2x1cm region), the other was found across all samples of the adult brain (but not found in other tissues such as Heart, Lung, etc.). The more restricted one (L1Hs#1) is inferred to have happened during the Fetal stage (first trimester) while the broader one happened earlier, approximately 2 weeks
post-fertilization. Overall the paper is clear, concise, and simple. It answers an interesting biological question: Can retrotransposition be used as a marker of cell clonal expansion? It does, although the retrotransposition frequency is very small and SNVs might support better results for the same analysis due to their higher frequency..