linkstream2 microblog

https://www.nytimes.com/2019/04/12/science/scott-kellys-photos-space.html

one end of the spectrum on open DNA

Let People Share DNA With a Click
https://www.bloomberg.com/opinion/articles/2019-01-22/the-nih-should-become-the-facebook-of-genome-data

liked particularly:

QT:[[”
3. Don’t go meta. Minimize concepts about concepts, like “approach, assumption, concept, condition, context, framework, issue, level, model, perspective, process, range, role, strategy, tendency,” and “variable.”

8. Old information at the beginning of the sentence, new information at the end.

10. Prose must cohere: readers must know how each sentence is related to the preceding one. If it’s not obvious, use “that is, for example, in general, on the other hand, nevertheless, as a result, because, nonetheless,” or “despite.”

12. Read it aloud.
“]]

https://boingboing.net/2019/03/27/here-are-cognitive-scientist-s.html

amusing…
The story has an interesting mendelian disease angle.
https://www.wired.com/story/scientists-need-more-cat-dna-and-lil-bub-is-here-to-help/

Scientists Need More Cat DNA, and Lil Bub is Here to Help
WIRED
Unusual DNA helped make Lil Bub a cat celebrity. Now that genetic data could improve medical care for cats without millions of Instagram followers. Read the full story

SCIENTIFIC AMERICAN MARCH 2019

Untangling the Formation of DNA Loops

New discoveries on ancient loops in DNA offer clues into gene regulation

By Erez Lieberman Aiden

https://www.scientificamerican.com/article/untangling-the-formation-of-dna-loops/

QT:[[”
“As he grew in his profession, Six came to feel he had a right to express himself on the family collection. A series of clashes with his father ensued, many of them about providing greater public access, which has always been a difficulty. Currently, tours of the
collection, which are by appointment only, are booked into next year. The picture that the younger Six sketched was of an inward-looking father who is trying to preserve a legacy by keeping the world at bay, who comes to realize over time that he also has to do battle with a gregarious and extroverted son who feels that the way to preserve that legacy is precisely by sharing it with the wider world. The battles left the younger Six progressively more exasperated: “I would cycle home after and think, Jesus, Dad, I’m trying to help you.””
“]]

Rembrandt in the Blood: An Obsessive Aristocrat, Rediscovered Paintings and an Art-World Feud
https://www.nytimes.com/2019/02/27/magazine/rembrandt-jan-six.html

https://www.nature.com/articles/s41586-019-0933-9

Using single-cell combinatorial indexing, we profiled the
transcriptomes of around 2 million cells derived from 61 embryos staged between 9.5 and 13.5 days of gestation, in a single experiment.

https://www.nature.com/articles/s41586-019-0969-x.epdf

QT:[[”
“The authors describe and validate a citation-based index of ‘disruptiveness’ that has previously been proposed for patents6. The intuition behind the index is straightforward: when the papers that cite a given article also reference a substantial proportion of that article’s references, then the article can be seen as consolidating its scientific domain. When the converse is true — that is, when future citations to the article do not also acknowledge the article’s own intellectual forebears — the article can be seen as disrupting its domain.

The disruptiveness index reflects a characteristic of the article’s underlying content that is clearly distinguishable from impact as conventionally captured by overall citation counts. For instance, the index finds that papers that directly contribute to Nobel prizes tend to exhibit high levels of disruptiveness, whereas, at the other extreme, review articles tend to consolidate their fields.”
“]]

http://www.nature.com/articles/d41586-019-00350-3

https://www.newyorker.com/magazine/2018/12/10/the-friendship-that-made-google-huge