linkstream2 microblog

https://www.ncbi.nlm.nih.gov/pubmed/9466909

https://www.autodeskresearch.com/publications/samestats

https://twitter.com/JustinMatejka/status/859075295059562498

great viz

Partitioning heritability of regulatory…variants across 11 common diseases http://www.Cell.com/ajhg/abstract/S0002-9297(14)00426-1 Almost 80% #noncoding v 10% coding

The paper below claims to find most of the heritability of 11 common diseases in regulatory regions (79% of heritability found in regulatory regions, <10% in protein coding regions).

Partitioning heritability of regulatory and cell-type-specific variants across 11 common
diseases.

Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium.

Am J Hum Genet. 2014 Nov 6;95(5):535-52. doi:
10.1016/j.ajhg.2014.10.004. Epub 2014 Nov 6.

also from ’14:
https://plus.google.com/+MarkGerstein/posts/D8kYoqiWL1P

Best Practices for Sci Computing
http://journals.PLOS.org/plosbiology/article?id=10.1371/journal.pbio.1001745 Usual stuff (GitHub, profilers, assertions) + some gems (turn bugs into test cases)

Best Practices for Sci Computing
http://journals.PLOS.org/plosbiology/article?id=10.1371/journal.pbio.1001745 Usual stuff (GitHub, profilers, assertions) + some gems (turn bugs into test cases)

can use w/ microSD
QT:{{”
Expand the phone’s 32GB memory+++ up to eight times with a 256GB microSD card. “}}

https://www.verizonwireless.com/smartphones/samsung-galaxy-s7/

The #Pangenome: Are Single Reference Genomes Dead? YES!
http://www.The-Scientist.com/?articles.view/articleNo/47510/title/The-Pangenome–Are-Single-Reference-Genomes-Dead-/ Division into conserved/core & dispensable/variable genes

Why Elephants Don’t Get Cancer – many TP53 copies
http://www.newsweek.com/2015/10/16/researchers-studying-elephants-improve-cancer-treatment-380822.html Result of #Peto’s Paradox: More cells don’t lead to more disease
see dog species

There are BrainSpan genotypes available through dbGAP:
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000406.v1.p1

https://www.google.com/search?q=graph+laplacian&ie=UTF-8&oe=UTF-8&hl=en-us&client=safari