linkstream2 microblog

http://www.bio-itworld.com/2018/05/09/carl-zimmer-to-speak-at-bio-it-world-tackle-heredity-genes-and-how-our-understanding-of-the-two-is-changing.aspx

QT:{{”
“It was a huge amount of fun watching them take that raw data and put it through their own pipelines,” Zimmer told me, but he also felt uncomfortable pointing out discrepancies to the scientists he worked with. “I still remember, I was sitting down with Chris Mason at Weill Cornell. He and his students were so enthusiastically going through their findings with me… and they showed me, among other things, how many SNPs I had. Not too long beforehand I’d gone through the same experience with Mark Gerstein and his team at Yale, and their numbers for my SNPs were off by hundreds of thousands. … It was a little awkward with Chris, but I just said, ‘Hey, I got a very different number from Mark Gerstein,’ and Chris just shrugged and said, ‘Oh yeah, that happens.’”

It turns out, there’s a lot about our current understanding of our genes and how we pass them on that isn’t perfectly clear cut. “}}

The Man Who Kicked Off…#Biotech by @CarlZimmer
http://nautil.us/issue/44/luck/the-man-who-kicked-off-the-biotech-revolution H Smith for discovering restriction enzymes + a history of the term

QT:{{”
“Trying to make sense of the failure, Wilcox suggested to Smith that the bacteria were destroying the viral DNA. He based his suggestion on a hypothesis proposed a few years earlier by Werner Arber, a microbiologist at the University of Geneva. Arber speculated that enzymes could restrict the growth of viruses by chopping up their DNA, and dubbed these hypothetical molecules “restriction enzymes.”” “}}

https://www.statnews.com/2016/08/17/genetic-variants-ex-ac-sequence/

http://blogs.plos.org/onscienceblogs/2016/07/15/scilogs-goes-kaput-game-of-genomes-is-an-ambitious-science-writing-oddity/

So the first part of the Zimmer article came out this morning. https://www.statnews.com/feature/game-of-genomes/season-one/

https://www.statnews.com/2016/07/05/game-of-genomes-trailer/

Growing Pains for Field of #Epigenetics by
@CarlZimmerhttp://www.nytimes.com/2016/07/02/science/epigenetic-marks-dna-genes.html Reflects well on overhype & correlation vs causation issues

Staying Afloat in the Rising Tide of Science by @CarlZimmer
http://www.Cell.com/cell/fulltext/S0092-8674(16)30192-1 How can this tide lift all boats & not drown us in Tb?

DNA Under the Scope &…Under a Cloud by @carlzimmer
http://www.nytimes.com/2016/02/27/science/dna-under-the-scope-and-a-forensic-tool-under-a-cloud.html Highlights the technical challenges of sequencing w/ few copies

http://www.cjr.org/the_profile/stat.php