linkstream2 microblog

https://www.nature.com/news/2010/100715/full/news.2010.356.html

QT:[[”

It should be possible to scan the genome for sequences encoding peptides shorter than 100 amino acids, says Mark Gerstein, a computational biologist at Yale University in New Haven, Connecticut, but sorting through the many ‘hits’ to determine which are functional is likely to be much more difficult.

Meanwhile, Gerstein notes that the polished rice peptides could also have implications for how we view pseudogenes, which have long been thought to be defunct relics of protein-coding genes. Pseudogenes often contain many signals that would stop protein synthesis and, as a result, could only encode short amino-acid chains. “Maybe this would provide a new way for pseudogenes to have some sort of function,” he says.
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The papers are out!
Using the tag pecrollout for this.
http://science.sciencemag.org/content/362/6420/1227

QT: {{”
The project’s namesake, ENCODE (Encyclopedia of DNA Elements), was a broader quest to map noncoding regions of the human genome. Its initial results, unveiled in 2012, stirred controversy. Scientists disputed the team’s claim that most of the genome was functional and questioned whether the project’s insights would be worth NIH’s $185 million investment (Science, 21 March 2014, p. 1306).
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The papers are out!
Using the tag pecrollout for this.
http://science.sciencemag.org/content/362/6420/1227

QT: {{”
The project’s namesake, ENCODE (Encyclopedia of DNA Elements), was a broader quest to map noncoding regions of the human genome. Its initial results, unveiled in 2012, stirred controversy. Scientists disputed the team’s claim that most of the genome was functional and questioned whether the project’s insights would be worth NIH’s $185 million investment (Science, 21 March 2014, p. 1306).
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http://www.facetsjournal.com/doi/full/10.1139/facets-2018-0002#.WzmasWXTsqo.twitter

To monitor the health of cities’ residents, look no further than their
sewers https://CEN.ACS.org/environment/water/monitor-health-citiesresidents-look-further/96/i18 Urban metabolism metrology & wastewater-based epidemiology. Big application is measuring illicit drugs. Interesting #privacy issues.

QT:{{”

“The oestrogen receptor achieves this by binding substances that contain a chemical structure called an aromatized A ring. Because oestrogens are the only steroid hormones to have such a ring, that criterion was enough to ensure that the receptor bound only oestrogens for many millions of years. Until, that is, the chemical industry started pumping out hundreds of substances containing such aromatized rings, which the oestrogen receptor unwittingly bound. “The endocrine disrupters are taking advantage, unfortunately, of the promiscuity that is the result of the evolutionary history of receptors,” Thornton says.”
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Prehistoric proteins: Raising the dead
http://www.nature.com/news/prehistoric-proteins-raising-the-dead-1.10261

https://www.wired.com/story/biology-will-be-the-next-great-computing-platform/

https://ai.googleblog.com/2018/05/duplex-ai-system-for-natural-conversation.html?m=

Google Duplex: An AI System for Accomplishing Real-World Tasks Over the Phone

Interesting paper by alumnus Renqiang Min on “Video Generation from Text,” using a generative #MachineLearning model.
http://www.AAAI.org/GuideBook2018/16152-72279-GB.pdf (Press report by @SilverJacket: New algorithm can create movies from just a few snippets of text
http://www.ScienceMag.org/news/2018/02/new-algorithm-can-create-movies-just-few-snippets-text )

Video Generation from Text Yitong Li†∗, Martin Renqiang Min‡ , Dinghan Shen† , David Carlson† , Lawrence Carin† †

http://www.newsweek.com/revolutionary-quantum-computer-one-step-closer-reality-after-major-836263