todo.txt (http://todotxt.com/).
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It is simple, light-weight and also has a ios app, which can sync using dropbox.
It is written using pure bash, and the best thing is that you can change the code and customize it if you want. You can also write/use plug-ins, and there are also all kind of community extension for the use on desktop, chrome and so on.
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Michael Bishop and Harold Varmus used an oncogenic retrovirus to identify the growth-controlling oncogenes in normal cells. In 1976 they published the remarkable conclusion that the oncogene in the virus did not represent a true viral gene but instead was a normal cellular gene, which the virus had acquired during replication in the host cell and thereafter carried along.
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http://www.nobelprize.org/nobel_prizes/medicine/laureates/1989/press.html
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Spiegelman worked on trying to establish that retroviruses cause human cancers. However, there were flaws in the theory.
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https://en.wikipedia.org/wiki/Howard_Martin_Temin
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Howard Martin Temin (December 10, 1934 – February 9, 1994) was a U.S. geneticistand virologist. He discovered reverse transcriptase in the 1970s[2] at the University of Wisconsin–Madison, for which he shared the 1975 Nobel Prize in Physiology or Medicine with Renato Dulbecco and David Baltimore.[3][4]
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The Avery–MacLeod–McCarty experiment was an experimental
demonstration, reported in 1944 by Oswald Avery, Colin MacLeod, andMaclyn McCarty, that DNA is the substance that causes bacterial transformation, in an era when it had been widely believed that it wasproteins that served the function of carrying genetic information (with the very word protein itself coined to indicate a belief that its function was primary).
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https://en.wikipedia.org/wiki/Theodor_Boveri
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Boveri’s work with sea urchins showed that it was necessary to have all chromosomespresent in order for proper embryonic development to take place. This discovery was an important part of the Boveri–Sutton chromosome theory. His other significant discovery was the centrosome (1888), which he described as the especial organ of cell division. Boveri also discovered the phenomenon of chromatin diminution during embryonic development of the nematode Parascaris.
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https://en.wikipedia.org/wiki/High-dose_chemotherapy_and_bone_marrow_transplant
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High–dose chemotherapy and bone marrow transplant (HDC/BMT), also high-dose … for megadose therapy in 1983. Frei and Peters developed the Solid Tumor Autologous Marrow Program (STAMP) regimen.
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Zebra is the American medical slang for arriving at an exotic medical diagnosis when a more commonplace explanation is more likely.[1] It is shorthand for the aphorism coined in the late 1940s by Dr. Theodore Woodward, professor at the University of Maryland School of Medicine, who instructed his medical interns: “When you hear hoofbeats, think of horses not zebras”.[2] Since horses are common in Maryland while zebras are relatively rare, logically one could confidently guess that an animal making hoofbeats is probably a horse. By 1960, the aphorism was widely known in medical circles.[3]
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https://en.m.wikipedia.org/wiki/Zebra_(medicine)
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To understand how this peculiar situation can come about, suppose you wanted to get from Atlanta to Cincinnati on February 6th. Delta is the only airline that flies direct between these cities, and this week the lowest one-way fare it was offering for that date was $251. However, Delta was also offering flights from Atlanta to Dallas with a stop in Cincinnati for just $197. Why? Because two other airlines also fly direct from Atlanta to Dallas, so price competition on that route is especially fierce. However, there is little to stop those wanting to go from Atlanta to Cincinnati from reserving an
Atlanta-Cincinnati-Dallas trip for $197 and simply ending their journey at the “hidden city” in the middle of their booking, saving $54.
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Phantom flights
http://www.economist.com/news/business/21639575-economics-air-ticketing-can-produce-some-peculiarities-phantom-flights @Skiplagged selling tickets A=>C w/ stop at B which are less than just A=>B; perverse incentives!
https://en.wikipedia.org/wiki/Susan_Sontag
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Sontag died in New York City on 28 December 2004, aged 71, from complications of myelodysplastic syndrome which had evolved into acute myelogenous leukemia.
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