http://www.stickwork.net/work/#/022017-sarah-p-duke-gardens-duke-university-durham-nc/
The Big Easy
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02/2017 The Big Easy, Sarah P Duke Gardens, Duke University, Durham, NC
Size: approximately 40’ X 20’ and 18’ tall
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.@GeoChurch ascribes his…ideas to narcolepsy
https://www.StatNews.com/2017/06/08/george-church-narcolepsy Advocates more neurodiversity, ie those w. ASD, OCD, ADD + narcolepsy
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“His condition has persuaded Church of the benefits of, even the need for, neurodiversity, meaning brains that work differently from most others. The world needs people with high-functioning autism and obsessive-compulsive disorder and attention deficit disorder and, yes, narcolepsy, he has come to believe.”
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Please find the article at link:
https://www.pharma-iq.com/informatics/articles/is-big-pharma-really-on-cusp-of-ai-shake-out-0
Is big pharma really on cusp of AI shake-out?
By: Pharma IQ
Posted: 07/14/2017
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The promises of “disruptive technologies” have failed to live up to expectations in the past. For example, the development of ‘high throughput screening’ – a process that employs robotics to conduct millions of chemical, genetic and pharmacological tests in rapid time – in the 1990s failed to significantly reduce R&D inefficiencies and offered sporadic success rates.
“The major cost in drug R&D is last-phase clinical trials,” said Dr Mark Gerstein, professor of biomedical informatics at Yale University. “It is not clear whether AI can be as useful for these as it has been in target selection for the initial phases.”
“One of the first principles of data mining is that history is a good predictor of the future. AI has a track record of not living up to its expectations and therefore caution about how great its impact will be in the healthcare industry is now warranted.”
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In Rural Oasis, #Serpico Finds New Adversaries
http://www.NYTimes.com/2013/07/05/nyregion/for-serpico-who-fought-police-corruption-a-new-conflict-over-woodland.html Famous cop from the past protecting #trees from a McMansion developer
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“But now Mr. Serpico’s serenity has been broken and he finds himself battling a new nemesis. This time, it is not an entire agency, but a local developer and town officials who Mr. Serpico says have ignored his complaints; this time, it is not over issues like taking cash payments from drug dealers, but over the fate of some trees and the desecration of pristine woodland.
“It’s like fighting the system again,” Mr. Serpico said. “Here I’m trying to enjoy my tranquillity and I’m being dragged back into a world of corruption.”
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Lame duck laureates
http://www.Economist.com/blogs/freeexchange/2013/08/nobel-prize-economics Interesting #bibliometric analysis of Nobelists: their normalized citations peak at the prize
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“The authors count the number of citations for each Nobel
prize-winner, using a service provided by JSTOR, a digital library. They look at what happens to Nobel prize-winners before and after they win their prizes. The data span from 1930 to 2005. One of the problems facing the authors was that, in 2005, there were many more JSTOR articles than in 1930. Therefore, raw citation numbers were
standardised by the total number of articles published in that year. The authors call the standardised units “Arrows”, after Kenneth Arrow, the economist who won the prize in 1972.”
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https://irp.nih.gov/catalyst/v19i4/germ-free-mice
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NIAID is home to one of the few facilities in the United States that houses so-called gnotobiotic mice. These mice are born in germ-free conditions, and investigators control the microbiota by inoculating the animals with specific microorganisms. The word “gnotobiotic” comes from the Greek words gnostos, for known, and bios, for life. “}}
https://www.ncbi.nlm.nih.gov/pubmed/11882781
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We find that over 600 positive associations between common gene variants and disease have been reported; these associations, if correct, would have tremendous importance for the prevention, prediction, and treatment of most common diseases. However, most reported associations are not robust: of the 166 putative associations which have been studied three or more times, only 6 have been consistently replicated.
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“The NCI will continue to supply the NCI-60 cell lines to researchers, but will eventually refocus its drug screening on newer models. It is developing hundreds of ‘patient-derived xenografts’ (PDXs), which are created by implanting small chunks of human tumours into mice. There, the tumours grow in an environment that, although not human, better mimics their native environment”
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$GOOG’s Road Map to Global Domination
http://www.NYTimes.com/2013/12/15/magazine/googles-plan-for-global-domination-dont-ask-why-ask-where.html Old article but discussion on #opendata v closed maps still relevant
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“O’Reilly is more skeptical. “An open-hardware play broke the IBM monopoly, an open-software play broke the Microsoft monopoly, and eventually an open-data play will prevail,” O’Reilly admits, but he points out that those earlier cases were not instances of direct competition between rival companies. “It wasn’t a plug-compatible mainframe clone that dethroned IBM; it wasn’t a free operating system like Linux that dethroned Windows.” Rather, he says, “it was this toy, the personal computer, it was the global operating system that we call the Internet.”
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