linkstream2 microblog

https://www.insidetracker.com/

A New Initiative on Precision Medicine
http://www.nejm.org/doi/full/10.1056/NEJMp1500523 Notable: focus on #cancergenomics & mention of endophenotypes & #QS data

Francis S. Collins, M.D., Ph.D., and Harold Varmus, M.D.
N Engl J Med 2015; 372:793-795February 26, 2015DOI: 10.1056/NEJMp1500523

QT:{{”
“These features make efforts to improve the ways we anticipate, prevent, diagnose, and treat cancers both urgent and promising. Realizing that promise, however, will require the many different efforts reflected in the President’s initiative. To achieve a deeper understanding of cancers and discover additional tools for molecular diagnosis, we will need to analyze many more cancer genomes. ….
The cancer-focused component of this initiative will be designed to address some of the obstacles that have already been encountered in “precision oncology”: unexplained drug resistance, genomic
heterogeneity of tumors, insufficient means for monitoring responses and tumor recurrence, and limited knowledge about the use of drug combinations.
…
The initiative’s second component entails pursuing research advances that will enable better assessment of disease risk, understanding of disease mechanisms, and prediction of optimal therapy for many more diseases, with the goal of expanding the benefits of precision medicine into myriad aspects of health and health care.

The initiative will encourage and support the next generation of scientists to develop creative new approaches for detecting, measuring, and analyzing a wide range of biomedical information — including molecular, genomic, cellular, clinical, behavioral, physiological, and environmental parameters. Many possibilities for future applications spring to mind: today’s blood counts might be replaced by a census of hundreds of distinct types of immune cells; data from mobile devices might provide real-time monitoring of glucose, blood pressure, and cardiac rhythm; genotyping might reveal particular genetic variants that confer protection against specific diseases…
“}}

http://twistedsifter.com/2014/12/guy-wears-heart-rate-monitor-during-proposal-and-graphs-results/

Cofounder Of 23andMe’s Next Project: Mining Your #QuantifiedSelf. @lindaavey’s @WeAreCurious creates a forum for this
http://www.fastcoexist.com/3027630/the-cofounder-of-23andmes-next-project-mining-your-quantified-self

Workouts are no antidote to death by desk: Great #graphics of writer v phys therapist daily exertion
http://www.newscientist.com/articleimages/mg21829232.200/1-workouts-are-no-antidote-to-death-by-desk-job.html via @mitchblunt

http://www.newscientist.com/article/mg21829232.200-workouts-are-no-antidote-to-death-by-desk-job.html

A Breathalyzer That Knows When You’re Burning Fat
Monitoring acetone in breath could tell dieters whether their efforts are paying off.
By Susan Young on August 8, 2013
http://www.technologyreview.com/news/517806/a-breathalyzer-that-knows-when-youre-burning-fat

Monitoring breath acetone with an iphone app tells about diabetes and whether exercise is burning fat
http://www.technologyreview.com/news/517806/a-breathalyzer-that-knows-when-youre-burning-fat #quantifiedself

http://gizmodo.com/5960507/watch-out-fitbit-here-comes-the-activity+tracking-shine

Next step for a #QuantifiedSelf: New sensor gives real time personal air quality assessments #NIH http://bit.ly/1beCjuQ via @NIHDirector
http://directorsblog.nih.gov/smart-clothes-a-wearable-air-quality-sensor/

What to get – fitbit’s better hardware v jawbone’s software? Also, there’s nike plus and there are rumors of a new one.
… bet they will all introduce new ones for the fall?
Wearable Devices Nudge You to a Healthier Lifestyle
http://www.nytimes.com/2013/06/27/technology/personaltech/wearable-devices-nudge-you-to-a-healthier-lifestyle.html
Fitbit’s hardware v Jawbone’s software? Also, Nike MT @nikohrdy: Wearable Devices Nudge You to Health http://bit.ly/11OZeYQ
#quantifiedself

Life logging… extreme but interesting
http://m.tuaw.com/2013/05/30/saga-lifelogging-app-captures-your-every-move