Posts Tagged ‘x78twee’

The 8q24 cancer risk variant rs6983267 shows long-range interaction with : MYC: in colorectal cancer : Abstract : Nature Genetics

Sunday, April 26th, 2015

Fighting a One-of-a-Kind Disease

Friday, October 24th, 2014

BMC Bioinformatics | Full text | GAPscreener: An Automatic Tool for Screening Human Genetic Association Literature in PubMed Using the Support Vector Machine Technique

Friday, October 24th, 2014

Is everything we eat associated with cancer? A systematic cookbook review

Friday, October 24th, 2014

Primates and mouse NumtS in the UCSC Genome Browser

Friday, October 24th, 2014 as ref. to current annotation in human

The genomic landscape of polymorphic human nuclear mitochondrial insertions | bioRxiv

Friday, October 24th, 2014

PLOS Computational Biology: Analysis of Stop-Gain and Frameshift Variants in Human Innate Immunity Genes

Friday, October 24th, 2014

Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data

Friday, October 24th, 2014 #ASHG14

mRNA surveillance mitigates genetic dominance … Mol Gen Genet. 1998 – PubMed – NCBI

Saturday, July 19th, 2014

Below is key ref.

## From Brenner talk at ISMB:

Argues that domain trunc prot have a dom. neg pheno.
(ex binding domain for reg & tf or sox10)

NMD fixes this; truncated case now looks like hemizyg.

## Related twitter dialogue:

Brenner: expl. how premature truncation is often a dominant neg. (ex SOX10), providing a rationalization for the purpose of NMD #ISMB #LBR01

@rtraborn · Jul 13
Why would cells generate mRNA that are then immediately degraded by NMD? Brenner suggests that this process has a regulatory function #ISMB

@raarjr · Jul 13
Brenner: 50 nt rule accurately predicts NMD, and is prevalent in auto what’s our ruler? #ismb

## REF

Mol Gen Genet. 1998 Nov;260(2-3):176-84.

mRNA surveillance mitigates genetic dominance in Caenorhabditis elegans.

Cali BM, Anderson P.

NeuroPID: a predictor for identifying neuropeptide precursors from metazoan proteomes

Saturday, July 19th, 2014

Linial: ClanTox ( to classify short peptides as toxins. #ismb #kn1

TOLIPS relevant to brain, neuropeptides

Linial mentions NeuroPID: a predictor for identifying neuropeptide precursors from metazoan proteomes #ismb #kn1