Posts Tagged ‘mynotes0mg’

Network propagation: a universal amplifier of genetic associations : Nature Reviews Genetics : Nature Research

Monday, September 11th, 2017

#Network propagation [by Markov walks, heat flow, diffusion, &c]: a universal amplifier of genetic associations
http://www.Nature.com/nrg/journal/v18/n9/abs/nrg.2017.38.html

Lenore Cowen,
Trey Ideker,
Benjamin J. Raphael
& Roded Sharan

http://www.nature.com/nrg/journal/v18/n9/abs/nrg.2017.38.html?foxtrotcallback=true

Protein Structural Memory Influences Ligand Binding Mode(s) and Unbinding Rates – Journal of Chemical Theory and Computation (ACS Publications)

Tuesday, September 5th, 2017

Structural Memory Influences Ligand-Binding Mode http://pubs.ACS.org/doi/abs/10.1021/acs.jctc.5b01052 Rearrangement of #solvation layer is ~100x slower than unbinding

J Chem Theory Comput. 2016 Mar 8;12(3):1393-9. doi:
10.1021/acs.jctc.5b01052. Epub 2016 Feb 3.

Xu M, Caflisch A, Hamm P.

Whole-genome landscapes of major melanoma subtypes : Nature : Nature Research

Tuesday, September 5th, 2017

Hayward, Nicholas K., et al. "Whole-genome landscapes of major melanoma subtypes." Nature 545.7653 (2017): 175-180.

Whole-genome landscapes of…#melanoma subtypes http://www.Nature.com/nature/journal/vaop/ncurrent/full/nature22071.html Sun-exposed cutaneous w. many C>T SNVs v acral/mucosal w. many SVs

Genome sequence-independent identification of RNA editing sites : Nature Methods : Nature Research

Monday, August 28th, 2017

http://www.nature.com/nmeth/journal/v12/n4/full/nmeth.3314.html

Genome seq–independent Identification of #RNAediting http://www.Nature.com/nmeth/journal/v12/n4/full/nmeth.3314.html Accurate sites from uncorrelated SNV pair, spanned by reads

Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells

Monday, August 14th, 2017

Naldi, A. et al. Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells. PLOS Computational Biology 13, e1005432 (2017).

Reconstruction & signal propagation analysis of the Syk signaling #network http://journals.PLoS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005432 Inferring potential targets of the kinase

Digital Health: Tracking Physiomes and Activity Using Wearable Biosensors Reveals Useful Health-Related Information

Tuesday, August 8th, 2017

http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2001402

#mHealth: Tracking Physiomes & Activity w/ Wearable Biosensors, by @SnyderShot et al http://journals.PLoS.org/plosbiology/article?id=10.1371/journal.pbio.2001402 >250K/day data pts on 43 people

Evaluation Of Chromatin Accessibility In Prefrontal Cortex Of Schizophrenia Cases And Controls | bioRxiv

Tuesday, August 1st, 2017

Eval of Chromatin Accessibility [via #ATACSeq] in DLPFC of SCZ Cases/Ctrls, by @JulienBryois et al.
http://www.BiorXiv.org/content/early/2017/05/25/141986 List of cQTLs

AI Pharma Innovation Summit 2017 – Final Event Information

Friday, July 28th, 2017

http://ai-pharma.com/event-guide/

https://linkstream2.gerstein.info/tag/i0aibos/

Whole-Genome Sequencing and Social-Network Analysis of a Tuberculosis Outbreak — NEJM

Sunday, July 23rd, 2017

WGS & Social-#Network Analysis of a TB Outbreak http://www.NEJM.org/doi/full/10.1056/NEJMoa1003176 Nice tech combo but not sure transmission & phylogeny are consistent

Thoughts on the PsychENCODE workshop & Psychiatric Genomics in the Era of Team Science – 2 recent DC meetings on Neurogenomics

Tuesday, July 11th, 2017

https://linkstream2.gerstein.info/tag/i0pec17/