Posts Tagged ‘from’
Accurate Prediction of Contact Numbers for Multi-Spanning Helical Membrane Proteins
Sunday, November 26th, 2017Accurate Prediction of Contact Numbers for Multi-Spanning Helical #MembraneProteins – via #NeuralNetwork w/ dropout
http://pubs.ACS.org/doi/abs/10.1021/acs.jcim.5b00517 In turn, this can enable accurate prediction of the rotation of TM helices & then the 3D #StructurePrediction of the whole protein
Atomic structure of the entire mammalian mitochondrial complex I | Nature
Sunday, November 26th, 2017Atomic structure of the entire mammalian mitochondrial complex I https://www.Nature.com/articles/nature19794 Synthesizing #cryoEM w/ (high-FP) cross-linking data to gets a 3.9A structure w/ 78 helices
Fiedorczuk, K., Letts, J.A., Degliesposti, G., Kaszuba, K., Skehel, M., Sazanov, L.A. (2016) Atomic structure of the entire mammalian mitochondrial complex I. Nature 538; 406-410.
related to:
• Letts, J.A., Fiedorczuk, K., Sazanov, L.A. (2016) The architecture of respiratory supercomplexes. Nature 537; 644-648.
The best automatic transcription tools for journalists | Poynter
Wednesday, November 22nd, 2017Dampen Noise with Custom-Made Window Inserts
Wednesday, November 22nd, 2017Quantifying the local resolution of cryo-EM density maps | Nature Methods
Wednesday, November 15th, 2017Quantifying the local resolution of #cryoEM density maps
https://www.Nature.com/articles/nmeth.2727 “Theory…based on the following idea: a L Angstrom feature exists at a pt…if a 3D local sinusoid of wavelength L is statistically detectable above noise at that point.”
QT:{{”
We propose a mathematical theory and an efficient algorithm for measuring local resolution that address all of the above limitations. The theory (Online Methods) is based on the following idea: a λ-Å feature exists at a point in the volume if a three-dimensional (3D) local sinusoid of wavelength λ is statistically detectable above noise at that point. A likelihood-ratio hypothesis test of the local sinusoid versus noise can detect this feature at a given P value (typically P = 0.05). We define the local resolution at a point as the smallest λ at which the local sinusoid is detectable, and we account for multiple testing with an FDR procedure.
“}}
Links to “Oncology at the Limits” and TRACERx Consortium
Sunday, November 5th, 2017…
Here is a link to the “Oncology at the Limits” Conference which is co-organised between UCL and Yale, …. It will be from
19th to 21st March at the Royal College of Physicians in London.
http://www.thelancet.com/education/at-the-limits/oncology-2017
The Keynote this year was … about the Lung TRACERx consortium. It is a project which
performs multi-site sampling of tumours to gain an insight into subclonal populations, and also follows up on the presence, expansion or response to therapy of these subclones via circulating-tumour-DNA. …
….
Car features
Sunday, October 29th, 2017Car safety features
Blind Spot Detection
Adaptive Cruise Control, Stop & Go, Low-speed follow
Lane Keep assist
Forward collision & braking
Pedestrian detection
Traffic sign recognition
Cross Traffic Monitor
Cross Traffic Braking
Front & Rear parking sensors
Driver awareness
Bird’s eye camera
Pre-tensioning
Collision avoidance steering
Turn assist
Side assist
Exit warning
Hood pedestrian safety system
Welcome | ScienceHill-CryoEM
Sunday, October 29th, 2017http://sciencehill-cryoem.yale.edu/
cryoem.yale.edu
https://medicine.yale.edu/ccmi/
Wikipedia shapes language in scientific papers
Friday, October 27th, 2017QT:{{"
"Wikipedia is one of the world’s most popular websites, but scientists rarely cite it in their papers. Despite this, the online encyclopedia seems to be shaping the language that researchers use in papers, according to an experiment showing that words and phrases in recently published Wikipedia articles subsequently appeared more frequently in scientific papers"
…
“Thompson and co-author Douglas Hanley, an economist at the University of Pittsburgh in Pennsylvania, commissioned PhD students to write 43 chemistry articles on topics that weren’t yet on Wikipedia. In January 2015, they published a randomized set of half of the articles to the site. The other half, which served as control articles, weren’t uploaded.
…
Using text-mining techniques to measure the frequency of words, they found that the language in the scientific papers drifted over the study period as new terms were introduced into the field. This natural drift equated to roughly one new term for every 250 words, Thompson told Nature. On top of those natural changes in language over time, the authors found that, on average, another 1 in every 300 words in a scientific paper was influenced by language in the Wikipedia article.”
"}}
#Wikipedia shapes lang. in science https://www.Nature.com/news/wikipedia-shapes-language-in-science-papers-1.22656 Seeding it with new pages & watching them evolve (v ctrls) as a type of soc. expt