Posts Tagged ‘fig’

PLOS Genetics: A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human Disease Mutations

Saturday, February 7th, 2015

Massively Parallel Pipeline to Clone DNA Variants & Examine…Disease
Mutations CloneSeq leverages NextGen sequencing

With the advance of sequencing technologies, tens of millions of genomic variants have been discovered in the human population. However, there is no available method to date that is capable of determining the functional impact of these variants on a large scale, which has increasingly become a huge bottleneck for the development of population genetics and personal genomics. Clone-seq and comparative interactome-profiling pipeline is a first to address this issue.

Can be coupled to many readouts.

Comment on “Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions ”

Saturday, May 18th, 2013

epigenomics data resource guide

Friday, June 22nd, 2012

The Epigenomics common fund project just published a guide to their project, describing the data and how to access the data.
Epigenomics. 2012 Jun;4(3):317-24.
The NIH Roadmap Epigenomics Program data resource.
Chadwick LH.