linkstream2 microblog

They published a paper on a web tool to generate box plots !! http://www.nature.com/nmeth/journal/v11/n2/full/nmeth.2811.html QT:{{”
Despite the obvious advantages of the box plot for simultaneous representation of data set and statistical parameters, this method is not in common use, in part because few available software tools allow the facile generation of box plots. For example, the standard spreadsheet tool Excel is unable to generate box plots.
…
M.S. and J.W. conceived of the box plot tool
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Related:
http://bioinformatics.oxfordjournals.org/content/early/2014/01/21/bioinformatics.btu038.abstract

QT:{{”
We discovered abundant (12 to 24%) monoallelic expression of autosomal genes and that expression of the two alleles occurs independently. The monoallelic expression appeared random and dynamic because there was considerable variation among closely related embryonic cells. “}}

A great article discussing the major issue of hyped social media presence:

“Social media makes it very easy for people to build a seemingly impressive persona by essentially ‘shouting louder’ than others. Having an opinion on something does not make one an expert.”

http://genomebiology.com/2014/15/7/424

The “Grep” Command But Not FusionMap, FusionFinder or ChimeraScan Captures the CIC-DUX4 Fusion Gene from Whole Transcriptome Sequencing Data on a Small Round Cell Tumor with t(4;19)(q35;q13)

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0099439

need adjusted p values after multiple hypothesis correction

Spurious Correlations
http://www.tylervigen.com

https://blog.twitter.com/2014/introducing-twitter-data-grants

we can play in meetings, and tell people we are working on cancer research.
http://scienceblog.cancerresearchuk.org/2014/02/04/download-our-revolutionary-mobile-game-to-help-speed-up-cancer-research

“Flexible isoform-level differential expression analysis with Ballgown” http://biorxiv.org/content/early/2014/03/30/003665

QT:{{”
We discovered abundant (12 to 24%) monoallelic expression of autosomal genes and that expression of the two alleles occurs independently. The monoallelic expression appeared random and dynamic because there was considerable variation among closely related embryonic cells. Similar patterns of monoallelic expression were observed in mature cells. Our allelic expression analysis also demonstrates the de novo inactivation of the paternal X chromosome.
“}}

http://www.sciencemag.org/content/343/6167/193.full

http://www.cancer.gov/cancertopics/understandingcancer/cancergenomics/AllPages