Archive for the ‘SciLit’ Category

Scientists discover an early modern human with a recent neanderthal ancestor

Friday, June 29th, 2018

https://phys.org/news/2015-07-scientists-early-modern-human-neanderthal.html

Genomic insights into the origin of farming in the ancient Near East

Friday, June 29th, 2018

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003663/

I. Lazaridis et al., “Genomic Insights into the Origin of Farming in the Ancient Near East,” Nature 536 (2016): 419–24

Genome-wide association study identifies 74 loci associated with educational attainment | Nature

Friday, June 29th, 2018

https://www.nature.com/articles/nature17671

Genome-wide association study identifies 74 loci associated with educational attainment

Aysu Okbay
, Jonathan P. Beauchamp
[…]
Daniel J. Benjamin

Nature 533, pages 539–542 (26 May 2016)

Ancient Admixture in Human History

Friday, June 29th, 2018

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522152/

Admixture, Population Structure, and F-Statistics

Friday, June 29th, 2018

Genetics. 2016 Apr; 202(4): 1485–1501.
Published online 2016 Feb 4. doi: 10.1534/genetics.115.183913 PMCID: PMC4905545
PMID: 26857625
Admixture, Population Structure, and F-Statistics
Benjamin M. Peter1

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905545/

The Genetic Legacy of the Mongols

Friday, June 29th, 2018

Am J Hum Genet. 2003 Mar; 72(3): 717–721.
Published online 2003 Jan 17. doi: 10.1086/367774
PMCID: PMC1180246
PMID: 12592608

The Genetic Legacy of the Mongols

Tatiana Zerjal,1 Yali Xue,1,2 Giorgio Bertorelle,3 R. Spencer Wells,4 Weidong Bao,1,5 Suling Zhu,1,5 Raheel Qamar,1,6Qasim Ayub,1,6 Aisha Mohyuddin,1,6 Songbin Fu,2 Pu Li,2 Nadira Yuldasheva,4,7 Ruslan Ruzibakiev,7 Jiujin Xu,5Qunfang Shu,5 Ruofu Du,5 Huanming Yang,5 Matthew E. Hurles,8 Elizabeth Robinson,1,* Tudevdagva
Gerelsaikhan,1,†Bumbein Dashnyam,9 S. Qasim Mehdi,5 and Chris Tyler-Smith1

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180246/

T. Zerjal et al., “The Genetic Legacy of the Mongols,” American Journal of Human Genetics 72 (2003): 717–21.

How reliable are empirical genomic scans for selective sweeps?

Thursday, June 21st, 2018

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1473181/

QT:{{”
One implication of these results is that, insofar as attributes of the beneficial mutation (e.g., the dominance coefficient) affect the power to detect targets of selection, genomic scans will yield an
unrepresentative subset of loci that contribute to adaptations. “}}

How reliable are empirical genomic scans for selective sweeps? Kosuke M. Teshima,1 Graham Coop, and Molly Przeworski1
Genome Res. 2006 Jun; 16(6): 702–712.
doi: 10.1101/gr.5105206
PMCID: PMC1473181
PMID: 16687733

Lessons from the Netflix prize challenge

Wednesday, June 20th, 2018

https://dl.acm.org/citation.cfm?id=1345465

The Cancer Genome Atlas: Creating Lasting Value beyond Its Data

Friday, June 15th, 2018

Commentary
The Cancer Genome Atlas: Creating Lasting Value beyond Its Data Carolyn Hutter + Jean Claude Zenklusen

https://www.sciencedirect.com/science/article/pii/S009286741830374X

Papers for Journal Club

Thursday, June 7th, 2018

Alternative evolutionary histories in the sequence space of an ancient protein https://www.Nature.com/articles/nature23902 Great viz of different potential but not necessarily realized evolutionary trajectories. Quite relevant for molecular #evolution & #pseudogenes