Archive for the ‘SciLit’ Category

Modern humans may be evolving to deal with carbohydrate-rich diets – Diet and evolution

Sunday, September 29th, 2019

Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism | eLife
https://elifesciences.org/articles/41517

Matteo Fumagalli, Stephane M Camus, Yoan Diekmann, Alice Burke, Marine D Camus, Paul J Norman, Agnel Joseph, Laurent Abi-Rached, Andrea Benazzo, Rita Rasteiro, Iain Mathieson, Maya Topf, Peter Parham, Mark G Thomas, Frances M Brodsky

evolutionary history CLTCL1 from 1000 genomes

https://www.economist.com/science-and-technology/2019/06/08/modern-humans-may-be-evolving-to-deal-with-carbohydrate-rich-diets

Modelling the recent common ancestry of all living humans | Nature

Sunday, September 29th, 2019

https://www.nature.com/articles/nature02842

Published: 30 September 2004

Modelling the recent common ancestry of all living humans
Douglas L. T. Rohde, Steve Olson & Joseph T. Chang

Avoiding the pitfalls of single particle cryo-electron microscopy: Einstein from noise | PNAS

Sunday, September 29th, 2019

Avoiding the pitfalls of single-particle #cryoEM: Einstein from noise https://www.PNAS.org/content/110/45/18037 A great paper, explaining in simple terms how you can fool yourself with fancy computer algorithms. However, perhaps it’s a bit too honest – only a Nobelist could write this!

Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects | Nature Communications

Tuesday, September 10th, 2019

https://www.nature.com/articles/s41467-018-06159-4

Artificial intelligence alone won’t solve the complexity of Earth sciences

Monday, September 2nd, 2019

Artificial intelligence alone won’t solve the complexity of Earth sciences http://www.nature.com/articles/d41586-019-00556-5

GWAS ATLAS resource

Saturday, August 24th, 2019

A global overview of pleiotropy and genetic architecture in complex traits

Kyoko Watanabe, Sven Stringer, Oleksandr Frei, Maša Umićević Mirkov, Christiaan de Leeuw, Tinca J. C. Polderman, Sophie van der Sluis, Ole A. Andreassen, Benjamin M. Neale & Danielle Posthuma

https://www.nature.com/articles/s41588-019-0481-0

Parental influence on human germline de novo mutations in 1,548 trios from Iceland. – PubMed – NCBI

Monday, August 19th, 2019

https://www.ncbi.nlm.nih.gov/pubmed/28959963

Genome-wide analysis of polymerase III-transcribed Alu elements suggests cell-type-specific enhancer function.

Sunday, August 18th, 2019

https://genome.cshlp.org/content/early/2019/08/14/gr.249789.119.long

A structural transition in physical networks | Nature

Monday, August 12th, 2019

https://www.nature.com/articles/s41586-018-0726-6

A structural transition in physical networks

Nima Dehmamy, Soodabeh Milanlouei & Albert-László Barabási

Naturevolume 563, pages676–680 (2018)

Quantifying the impact of public omics data.

Sunday, August 11th, 2019

similar idea to quantifying the value of the data
https://www.ncbi.nlm.nih.gov/pubmed/31383865