Archive for November, 2017

ERCC9 – exRNA

Sunday, November 19th, 2017

https://exrna.org/ercc9/

Access to genomes of supercentenarians

Sunday, November 19th, 2017

https://www.nytimes.com/2017/11/13/health/supercentenarians-genetics-longevity.html

authoera vs googledoc

Sunday, November 19th, 2017

https://www.authorea.com/users/3/articles/6055-how-is-authorea-different-from-google-docs

Winds of change – Infographics

Sunday, November 19th, 2017

Winds of change
https://www.Economist.com/news/books-and-arts/21580446-revolution-taking-place-how-visualise-information-winds-change Good quotes on #InfoGraphics: “Visualization is a continuous spectrum that stretches from statistical graphics to #dataart” + “Data journalism, the idea is that reporters must interrogate both people & databases…to get their information.”

QT:{{”
For that is what data-visualisations are: a blend of the aesthetic and informational. Having one without the other means producing something that is less useful and enjoyable than it might be, argues Nathan Yau, a statistician who runs a blog called FlowingData.com. Visualisation is a whole new medium, he writes in his new book, “Data Points”. It is a “continuous spectrum that stretches from statistical graphics to data art”.

“Data Points” is a useful primer for those who need to produce infographics. But for those who merely want to appreciate them, two other books fit the bill, both by Guardian journalists.

In recent years the London-based daily newspaper has promoted a new area called “data journalism”. The idea is that reporters must interrogate both people and databases in order to get their
information. Simon Rogers’s “Facts Are Sacred” is a review of the past few years’ worth of this data journalism on the paper’s website. It brings together some of its best projects and explains how they were done.
“}}

NOT-OD-17-110: Request for Comments: Proposal to Update Data Management of Genomic Summary Results Under the NIH Genomic Data Sharing Policy

Saturday, November 18th, 2017

https://grants.nih.gov/grants/guide/notice-files/NOT-OD-17-110.html

Sent from my iPad

Antibodies and how they fight disease – The Washington Post

Saturday, November 18th, 2017

https://www.washingtonpost.com/national/health-science/a-fascinating-look-at-antibody-based-technology-really/2017/10/27/f016894a-b987-11e7-9e58-e6288544af98_story.html?utm_term=.88be6d036a39

NOT-OD-17-110: Request for Comments: Proposal to Update Data Management of Genomic Summary Results Under the NIH Genomic Data Sharing Policy

Saturday, November 18th, 2017

https://grants.nih.gov/grants/guide/notice-files/NOT-OD-17-110.html

The future of DNA sequencing

Wednesday, November 15th, 2017

The Future of DNA Seq.
http://www.Nature.com/news/the-future-of-dna-sequencing-1.22787 Apps v Tech. QT: “Platforms for…#sequencing have changed dramatically…Yet the trajectories of other technologies…Internet, digital
photography…suggest…real disrupters will be the resulting applications, not the new tech”

QT:{{”
Killer applications –
Over the years, the platforms for DNA sequencing have changed dramatically (see ”). Yet the trajectories of other technologies for which there is a seemingly insatiable demand — smartphones, the Internet, digital photography — suggest that the real disrupters will be the resulting applications, not the new technologies.

“}}

Quantifying the local resolution of cryo-EM density maps | Nature Methods

Wednesday, November 15th, 2017

Quantifying the local resolution of #cryoEM density maps
https://www.Nature.com/articles/nmeth.2727 “Theory…based on the following idea: a L Angstrom feature exists at a pt…if a 3D local sinusoid of wavelength L is statistically detectable above noise at that point.”

QT:{{”
We propose a mathematical theory and an efficient algorithm for measuring local resolution that address all of the above limitations. The theory (Online Methods) is based on the following idea: a λ-Å feature exists at a point in the volume if a three-dimensional (3D) local sinusoid of wavelength λ is statistically detectable above noise at that point. A likelihood-ratio hypothesis test of the local sinusoid versus noise can detect this feature at a given P value (typically P = 0.05). We define the local resolution at a point as the smallest λ at which the local sinusoid is detectable, and we account for multiple testing with an FDR procedure.
“}}

If we only ate organic it would be an environmental disaster | New Scientist

Wednesday, November 15th, 2017

https://www.newscientist.com/article/2153272-if-we-only-ate-organic-it-would-be-an-environmental-disaster/