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Archive for February, 2017

How DNA Editing Could Change Life on Earth

Thursday, February 23rd, 2017

QT:{{”
“One of Esvelt’s goals at M.I.T. is to facilitate that shift. Part of his job, as he sees it, is to challenge what he describes as “the ridiculous notion that natural and good are the same thing.” Instead, he told me, we ought to think about intelligent design as an instrument of genetics. He smiled because the phrase “intelligent design” usually refers to the anti-Darwinian theory that the universe, with all its intricacies and variations, is too complex to have arisen by chance—that there had to be a guiding hand. The truth is more prosaic, and also more remarkable: for four billion years, evolution, driven by natural selection and random mutation, has insured that the most efficient genes would survive and the weakest would disappear. But, propelled by CRISPR and other tools of synthetic biology, intelligent design has taken on an entirely new meaning, one that threatens to transcend Darwin—because evolution may soon be guided by us.”
“}}

How DNA Editing Could Change Life on Earth
http://www.NewYorker.com/magazine/2017/01/02/rewriting-the-code-of-life Intelligent design from CRISPR & gene drive rather than natural selection

Posted in PopSci | Tags: crispr, genedrive, quote, x57s | No Comments »

interesting paper

Thursday, February 23rd, 2017

Partitioning heritability of regulatory…variants across 11 common diseases http://www.Cell.com/ajhg/abstract/S0002-9297(14)00426-1 Almost 80% #noncoding v 10% coding

The paper below claims to find most of the heritability of 11 common diseases in regulatory regions (79% of heritability found in regulatory regions, <10% in protein coding regions).

Partitioning heritability of regulatory and cell-type-specific variants across 11 common
diseases.

Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium.

Am J Hum Genet. 2014 Nov 6;95(5):535-52. doi:
10.1016/j.ajhg.2014.10.004. Epub 2014 Nov 6.

Posted in SciLit | Tags: email, from, from_email, noncoding, psychencode, x57l | No Comments »

The complete list of Siri commands – CNET

Monday, February 20th, 2017

Some ones l liked.

QT:{{”

Schedule or cancel a meeting. Ex.: “Schedule a meeting with [name] tomorrow at 11:30 a.m.” or “Cancel my 5 p.m. appointment.”

Set location-aware reminders. Ex.: “Remind me to remember my keys when I leave,” or “Remind me to feed the dog when I get home.”

Set alarms. Ex.: “Set an alarm for 1 a.m.” or “Set an alarm for six hours from now.”

Delete/turn off all alarms. Ex. “Delete all alarms” or “Turn off all alarms.”

Check the number of days between dates. Ex.: “How many days until October 6?” or “How many days between April 3 and June 16?”

Send an email. Ex.: “Send email to [name] about [subject] and say [message].”

Set a timer. Ex.: “Set the timer for 10 minutes.”
Check the weather. Ex.: “What’s the weather like today?” or “Do I need an umbrella?”

Random tips and tricks:

Find out what airplanes are currently flying above you. Ex.: “What airplanes are above me?”
Roll a die or roll two dice.
Tell me a joke.
What does the fox say?
Knock knock.
Who’s on first?
Why did the chicken cross the road?
What is zero divided by zero?
Learn how to say my name.
“}}

https://www.cnet.com/how-to/the-complete-list-of-siri-commands/

Posted in Hint | Tags: quote, siri, x57s, x58f | No Comments »