linkstream2 microblog

http://www.forbes.com/sites/stevensalzberg/2014/09/28/is-sitting-at-your-desk-killing-you/

http://linkstream2.gerstein.info/tag/i0dataday
http://elischolar.library.yale.edu/dayofdata/2014/
https://storify.com/markgerstein/tweets-related-to-the-yale-day-of-data-2014-ydod20

Coppi mentions: JHU’s Data-scope (http://idies.jhu.edu/datascope ), which has a specialized architecture for astronomical computation #ydod2014

4 PB / yr

Bourne mentions “What Big Data means to me”
(http://jamia.bmj.com/content/21/2/194.extract ) in connection with the creation of a digital ecosystem #ydod2014

http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3101.html

An interesting report of potential non-coding drivers without actually doing any wet lab work.

“These methods identify recurrent mutations in regulatory elements upstream of PLEKHS1, WDR74 and SDHD, as well as previously identified mutations in the TERT promoter”. In the text they mention “Khurana et al. also reported WDR74 promoter mutations in 2 of the 20 prostate cancer genomes analyzed”.

Nice viz of the quality of a single sequencing run
{Disclaimer I’m a consultant to this company.}

http://help.bina.com/demo/#/quality_report

Spatial Generalization in… Learning: Lessons from… #Basketball http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1003623 How past success changes your tendencies to shoot

Describes constructing a learning matrix for how a player will update his tendency to shoot
from a certain region of the court based on his past successes or failures

Parable of #Google Flu: Traps in #BigData Analysis http://www.sciencemag.org/content/343/6176/1203.summary Replicating results is hard, w/ an ever-changing search algorithm

Mentions http://www.google.com/trends/correlate

For #BigData Scientists, Janitor Work Is Key http://www.nytimes.com/2014/08/18/technology/for-big-data-scientists-hurdle-to-insights-is-janitor-work.html Is a #datascientist a digital maid or a data priest? Perhaps a hybrid.

O’Neil talk

Splicing changes along the blood lineage, good ex. of the
state-of-the-art in human transcriptomics
http://www.sciencemag.org/content/345/6204/1251033.abstract

Science 26 September 2014:
Vol. 345 no. 6204
DOI: 10.1126/science.1251033

Transcriptional diversity during lineage commitment of human blood progenitors

Chen et al.