Posts Tagged ‘from’
GPS4CAM
Tuesday, July 5th, 2016Predicting peptide binding sites on protein surfaces by clustering chemical interactions – Yan – 2014 – Journal of Computational Chemistry – Wiley Online Library
Monday, July 4th, 2016Predicting peptide binding sites on protein surfaces by ACCLUSTER http://onlinelibrary.wiley.com/doi/10.1002/jcc.23771/abstract #Chemical interactions out perform pure #packing
Single-Cell Co-expression Analysis Reveals Distinct Functional Modules, Co-regulation Mechanisms and Clinical Outcomes
Saturday, July 2nd, 2016#SingleCell Coexpression…Reveals Distinct Func. Modules [v clustering bulk RNAseq]… & Clinical Outcomes [in GBM]
http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004892
QT:{{”
We found that the co-expressed genes observed in single cells and bulk tumors have little overlap and show distinct characteristics. The co-expressed genes identified in bulk tumors tend to have similar biological functions, and are enriched for intrachromosomal
interactions with synchronized promoter activity. In contrast, single-cell co-expressed genes are enriched for known protein-protein interactions, and are regulated through interchromosomal interactions. “}}
Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling: Cell
Saturday, July 2nd, 2016Kinome-wide Decoding of #Network-Attacking Mutations Rewiring Cancer http://www.cell.com/cell/abstract/S0092-8674(15)01108-3 Mapping NAMs onto well-known signaling pathways
Tempus – Buying Time
Saturday, June 18th, 2016The Independent Discovery of TCP/IP, By Ants
Saturday, June 18th, 2016The Independent Discovery of TCP/IP, By Ants
http://priceonomics.com/the-independent-discovery-of-tcpip-by-ants/ Protocol has similarities to #ant communication; man reinventing nature
How does multiple testing correction work?
Monday, June 13th, 2016How does multiple-testing correction work
http://www.nature.com/nbt/journal/v27/n12/abs/nbt1209-1135.html Intuition for teaching: genome-wide error rate on a single gene v family
The role of regulatory variation in complex traits and disease : Nature Reviews Genetics : Nature Publishing Group
Sunday, June 12th, 2016Reg. variation in cplx traits by @LeonidKruglyak
http://www.nature.com/nrg/journal/v16/n4/full/nrg3891.html nice teaching figure for #eQTLs, showing how mostly cis + hotspots http://www.nature.com/nrg/journal/v16/n4/full/nrg3891.html