linkstream2 microblog

https://www.smithsonianmag.com/science-nature/artificial-intelligence-study-human-genome-finds-unknown-human-ancestor-species-180971436/#ppY5jy9gT2zYRh6U.99

QT:((”
“Let me get the most important question out of the way: is AlphaFold’s advance really significant, or is it more of the same? I would characterize their advance as roughly two CASPs in one (really ~1.8x). Historically progress in CASP has ebbed and flowed, with a ten year period of almost absolute stagnation, finally broken by the advances seen at CASP11 and 12, which were substantial. What we’ve seen this year is roughly twice as much as the recent average rate of advance (measured in mean ΔGDT_TS from CASP10 to CASP12—GDT_TS is a measure of prediction accuracy ranging from 0 to 100, with 100 being perfect.) As I will explain later, there may actually be a good reason for this “two CASPs” effect, in terms of the underlying methodological breakdown. This can be seen not only in the CASP-over-CASP
improvement, but also in terms of the size of the gap between AlphaFold and the second best performer, which is unusually large by CASP standards. Below is a plot that depicts this.”
“))

https://moalquraishi.wordpress.com/2018/12/09/alphafold-casp13-what-just-happened/

QT:((”
““The only thing that matters is the future,” he told me after the civil trial was settled. “I don’t even know why we study history. It’s entertaining, I guess—the dinosaurs and the Neanderthals and the Industrial Revolution, and stuff like that. But what already happened doesn’t really matter. You don’t need to know that history to build on what they made. In technology, all that matters is tomorrow.” “))

https://www.newyorker.com/magazine/2018/10/22/did-uber-steal-googles-intellectual-property

https://en.wikipedia.org/wiki/Glory_Days_(Bruce_Springsteen_song)

http://theconversation.com/life-expectancy-in-britain-has-fallen-so-much-that-a-million-years-of-life-could-disappear-by-2058-why-88063

https://www.nytimes.com/2019/01/30/well/move/can-low-impact-sports-like-cycling-be-putting-your-bones-at-risk.html?smid=tw-nytimes&smtyp=cur

https://www.scientificamerican.com/article/how-machine-learning-could-keep-dangerous-dna-out-of-terrorists-hands

https://en.wikipedia.org/wiki/Mediation_(statistics)

QT:((”
Intuitively, IVs are used when an explanatory variable of interest is correlated with the error term, in which case ordinary least squares and ANOVA give biased results.
“))

https://en.wikipedia.org/wiki/Instrumental_variables_estimation

https://www.theatlantic.com/science/archive/2019/02/deadly-mushroom-arrives-canada/581602