Archive for the ‘SciLit’ Category

Mirsynergy: detecting synergistic miRNA regul… Bioinformatics. 2014 – PubMed – NCBI

Saturday, July 19th, 2014

Mirsynergy: detecting synergistic #miRNA regulatory modules by… neighborhood expansion
http://www.ncbi.nlm.nih.gov/pubmed/24894504 creates overlapping clusters

Ensemble Methods in Machine Learning. Proceedings of the First International Workshop on Multiple Classifier Systems

Sunday, July 13th, 2014

Rich C, Alexandru N-M, Geoff C, Alex K (2004) Ensemble selection from libraries of
models. Proceedings of the twenty-first international conference on Machine learning. Banff, Alberta, Canada: ACM.
http://www.niculescu-mizil.org/papers/shotgun.icml04.revised.rev2.pdf

Thomas GD (2000) Ensemble Methods in Machine Learning. Proceedings of the First International Workshop on Multiple Classifier Systems: Springer-Verlag.
http://www.eecs.wsu.edu/~holder/courses/CptS570/fall07/papers/Dietterich00.pdf http://dl.acm.org/citation.cfm?id=743935

.@deniseOme Good ref is TG Dietterich #Ensemble Methods in
#MachineLearning MCS ’00
http://www.eecs.wsu.edu/~holder/courses/CptS570/fall07/papers/Dietterich00.pdf Not rel. to @ensembl #ismb #afp14

ref 17 & 18

BMC Bioinformatics | Full text | A new measure for functional similarity of gene products based on Gene Ontology

Saturday, July 12th, 2014

BMC Bioinformatics | Full text | A new measure for functional similarity of gene products based on Gene Ontology
http://www.biomedcentral.com/1471-2105/7/302

Related to:
http://papers.gersteinlab.org/papers/funcsim/

Information-theoretic evaluation of predicted ontological annotations

Saturday, July 12th, 2014

http://bioinformatics.oxfordjournals.org/content/29/13/i53.short

Predicting phenotype from patterns of annotation

Saturday, July 12th, 2014

Roth lab paper
http://bioinformatics.oxfordjournals.org/content/19/suppl_1/i183.long

Manual curation is not sufficient for annotation of genomic databases

Saturday, July 12th, 2014

Hunter lab pub

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516305/

PLOS ONE: The Impact of Multifunctional Genes on “Guilt by Association” Analysis

Saturday, July 12th, 2014

Pavlidis mentions: …Multifunctional Genes…
http://www.plosone.org/article/info%253Adoi%252F10.1371%252Fjournal.pone.0017258 … hubbiness predicts these better than more complex methods #ismb #afp14

Network Biology Publications

Saturday, July 12th, 2014

http://netbiopub.tumblr.com
associated w/ linkedin group

Reference “Quantifying reproducibility in computational biolo…”

Friday, July 11th, 2014

PLoS ONE, 2013 vol. 8(11) pp. e80278

Quantifying reproducibility in computational biology: the case of the tuberculosis drugome.
http://www.ncbi.nlm.nih.gov/pubmed/24312207

Garijo, D; Kinnings, S; Xie, L; Xie, L; Zhang, Y; Bourne, PE; Gil, Y
QT:{{
How easy is it to reproduce the results found in a typical computational biology paper? Either through experience or intuition the reader will already know that the answer is with difficulty or not at all. In this paper we attempt to quantify this difficulty by reproducing a previously published paper for different classes of users (ranging from users with little expertise to domain experts) and suggest ways in which the situation might be improved. Quantification is achieved by estimating the time required to reproduce each of the steps in the method described in the original paper and make them part of an explicit workflow that reproduces the original results. Reproducing the method took several months of effort, and required using new versions and new software that posed challenges to reconstructing and validating the results. The quantification leads to "reproducibility maps" that reveal that novice researchers would only be able to reproduce a few of the steps in the method, and that only expert researchers with advance knowledge of the domain would be able to reproduce the method in its entirety. ….
}}

.@pebourne Perhaps we need to educate biomedical data PhD students for more diverse careers #ismb #AFP14

PLOS Biology: The Ecology of Collective Behavior

Friday, July 11th, 2014

#Ecology of Collective Behavior
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001805 #Network structure reflects resource patchiness, operating costs & threat of rupture