Dunbrack PhD thesis
http://www.sciencedirect.com/science/article/pii/S0022283683711708?via=ihub Backbone-dependent Rotamer Library for Proteins Application to Side-chain Prediction — ScienceDirect
Maps of protein structure space reveal a fundamental relationship between protein structure and function
http://www.pnas.org/content/108/30/12301.abstract
Mapping functional transcription factor networks from gene expression data
NetProphet ref
Large-scale reconstruction of 3D structures of human chromosomes from chromosomal contact data
http://nar.oxfordjournals.org/content/early/2014/01/24/nar.gkt1411.full
Mol Biosyst. Author manuscript; available in PMC Jul 1, 2014. Published in final edited form as:
Mol Biosyst. Jan 2014; 10(1): 9–17.
doi: 10.1039/c3mb70225a
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710751/
surprisingly, no positional effects on LOF mutations … significant proportion of truncation alleles give rise to functional products
“guilt by assoc works”
signif. number dom mut give rise to func products
High-throughput functional testing of ENCODE segmentation predictions
http://genome.cshlp.org/content/early/2014/07/17/gr.173518.114.abstract?papetoc