Archive for the ‘SciLit’ Category

Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells

Monday, August 14th, 2017

Naldi, A. et al. Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells. PLOS Computational Biology 13, e1005432 (2017).

Reconstruction & signal propagation analysis of the Syk signaling #network http://journals.PLoS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005432 Inferring potential targets of the kinase

Digital Health: Tracking Physiomes and Activity Using Wearable Biosensors Reveals Useful Health-Related Information

Tuesday, August 8th, 2017

http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2001402

#mHealth: Tracking Physiomes & Activity w/ Wearable Biosensors, by @SnyderShot et al http://journals.PLoS.org/plosbiology/article?id=10.1371/journal.pbio.2001402 >250K/day data pts on 43 people

Evaluation Of Chromatin Accessibility In Prefrontal Cortex Of Schizophrenia Cases And Controls | bioRxiv

Tuesday, August 1st, 2017

Eval of Chromatin Accessibility [via #ATACSeq] in DLPFC of SCZ Cases/Ctrls, by @JulienBryois et al.
http://www.BiorXiv.org/content/early/2017/05/25/141986 List of cQTLs

Whole-Genome Sequencing and Social-Network Analysis of a Tuberculosis Outbreak — NEJM

Sunday, July 23rd, 2017

WGS & Social-#Network Analysis of a TB Outbreak http://www.NEJM.org/doi/full/10.1056/NEJMoa1003176 Nice tech combo but not sure transmission & phylogeny are consistent

Post-transcriptional regulation across human tissues

Sunday, July 16th, 2017

Post-transcriptional reg…across…tissues [v genes], by @SlavovLab http://journals.PLoS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005535 Simpson’s paradox! Diff in protein-mRNA corr.

Post-transcriptional regulation across human tissues

Sunday, July 16th, 2017

Post-transcriptional reg…across…tissues [v genes], by @SlavovLab http://journals.PLoS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005535 Simpson’s paradox! Diff in protein-mRNA corr.

[tags prot-v-mrna,pare,SlavovLab,simpsonsparadox,nida2,x57l]

Post-transcriptional regulation across human tissues

Sunday, July 16th, 2017

Post-transcriptional reg…across…tissues [v genes], by @SlavovLab http://journals.PLoS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005535 Diff in protein-mRNA corr. Simpson’s paradox![tags prot-v-mrna,pare,SlavovLab,simpsonsparadox,nida2,x57l]

The Cellular and Molecular Landscapes of the Developing Human Central Nervous System

Monday, July 10th, 2017

https://www.researchgate.net/publication/291391911_The_Cellular_and_Molecular_Landscapes_of_the_Developing_Human_Central_Nervous_System

good dev fig?

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. – PubMed – NCBI

Monday, July 10th, 2017

https://www.ncbi.nlm.nih.gov/pubmed/24267887

Cell. 2013 Nov 21;155(5):1008-21. doi: 10.1016/j.cell.2013.10.031.

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism.

Parikshak NN1, Luo R, Zhang A, Won H, Lowe JK, Chandran V, Horvath S, Geschwind DH.

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies : Nature Genetics : Nature Research

Monday, July 10th, 2017

http://www.nature.com/ng/journal/v47/n3/full/ng.3211.html