Archive for July, 2017

Startup Founder’s Quest for Cure Leads to Genomics Hackathon at Google | Xconomy

Thursday, July 27th, 2017

http://www.xconomy.com/san-francisco/2017/06/23/startup-founders-quest-for-cure-leads-to-genomics-hackathon-at-google/

10 Places With Spectacular Views Of This Summer’s Total Solar Eclipse

Thursday, July 27th, 2017

https://www.buzzfeed.com/zahrahirji/spectacular-views-of-the-eclipse?utm_term=.gypx1PMo2#.hnrPwBdNW

Microchip Implants for Employees? One Company Says Yes – The New York Times

Tuesday, July 25th, 2017

https://www.nytimes.com/2017/07/25/technology/microchips-wisconsin-company-employees.html?smid=tw-share

Are You a Carboholic? Why Cutting Carbs Is So Tough – The New York Times

Tuesday, July 25th, 2017

QT:{{”
The conventional thinking, held by the large proportion of the many researchers and clinicians I’ve interviewed over the years, is that obesity is caused by caloric excess. They refer to it as an “energy balance” disorder, and so the treatment is to consume less energy (fewer calories) and expend more. When we fail to maintain this prescription, the implication is that we simply lack will power or self-discipline.

“It’s viewed as a psychological issue or even a question of
character,” says Dr. David Ludwig, who studies and treats obesity at Harvard Medical School.

The minority position in this field — one that Dr. Ludwig holds, as do I after years of reporting — is that obesity is actually a hormonal regulatory disorder, and the hormone that dominates this process is insulin. It directly links what we eat to the accumulation of excess fat and that, in turn, is tied to the foods we crave and the hunger we experience. It’s been known since the 1960s that insulin signals fat cells to accumulate fat, while telling the other cells in our body to burn carbohydrates for fuel. By this thinking these carbohydrates are uniquely fattening.

“}}

Are You a Carboholic? Why Cutting #Carbs Is So Tough
https://www.NYTimes.com/2017/07/19/well/eat/are-you-a-carboholic-why-cutting-carbs-is-so-tough.html #Obesity as an energy-balance v hormonal-regulatory disorder

Robert Caro Fourth Volume – The Big Book, by Chris Jones – Esquire

Tuesday, July 25th, 2017

The Big Book http://www.Esquire.com/features/robert-caro-0512 Great description of a clinical & cool but productive 4-decade relationship betw. R #Caro & his editor

LBJ #4

QT:{{”
“Gottlieb did the same math and agreed. In an industry that survives mostly by lying to itself, he is an anti-romantic, an
unsentimentalist. When he edits Caro, they sit side by side at a conference table and go through the pile in front of them, page by tattered page, Gottlieb attacking anything that reads too much like writing, too much like nostalgia or indulgence. He and Caro have mellowed with age, but they have fought bitter fights, fights that have caused people to close their office doors hundreds of feet away. “Everything to him is as serious as everything else,” Gottlieb says. “When we came to something like a semicolon, it was war.”

…Gottlieb is the taskmaster. (“I can remember when he told me, ‘Not bad,’ ” Caro says. “Once.”) Gottlieb and Caro, bound for forty years, rarely see each other socially. Theirs is a professional relationship, clear-eyed and clinical.

Yet they are also prisoners of a mutual faith. “Bob is convinced that without me, he cannot function,” Gottlieb says. “I have explained to him for years that it isn’t the truth. It isn’t the truth. But because he believes it to be true, it is true.” And Gottlieb has given over so much of his own life to Caro, has fought so hard over semicolons, because he believes something else to be true. “These books will live forever,” Gottlieb says. “We all know that.””
“}}

Robert Caro Fourth Volume – The Big Book, by Chris Jones – Esquire

Tuesday, July 25th, 2017

The Big Book http://www.Esquire.com/features/robert-caro-0512 Great description of a clinical & cool but productive 4-decade relationship betw. R #Caro & his editor

LBJ #4

QT:{{”
“Gottlieb did the same math and agreed. In an industry that survives mostly by lying to itself, he is an anti-romantic, an
unsentimentalist. When he edits Caro, they sit side by side at a conference table and go through the pile in front of them, page by tattered page, Gottlieb attacking anything that reads too much like writing, too much like nostalgia or indulgence. He and Caro have mellowed with age, but they have fought bitter fights, fights that have caused people to close their office doors hundreds of feet away. “Everything to him is as serious as everything else,” Gottlieb says. “When we came to something like a semicolon, it was war.”

…Gottlieb is the taskmaster. (“I can remember when he told me, ‘Not bad,’ ” Caro says. “Once.”) Gottlieb and Caro, bound for forty years, rarely see each other socially. Theirs is a professional relationship, clear-eyed and clinical.

Yet they are also prisoners of a mutual faith. “Bob is convinced that without me, he cannot function,” Gottlieb says. “I have explained to him for years that it isn’t the truth. It isn’t the truth. But because he believes it to be true, it is true.” And Gottlieb has given over so much of his own life to Caro, has fought so hard over semicolons, because he believes something else to be true. “These books will live forever,” Gottlieb says. “We all know that.””
“}}

2 Ways to Use a Custom Domain with Dropbox – fredericiana

Tuesday, July 25th, 2017

http://fredericiana.com/2012/12/09/custom-domain-with-dropbox/

QT:{{"

Option 2: CNAME

There’s another option that doesn’t require any changes to your server. However, you’ll need access to your provider’s DNS settings.

If you do have such access, you can create a DNS CNAME record. A CNAME record is essentially a domain alias, forwarding one domain name to another.

It’s pretty simple:

  1. Access your provider’s DNS settings menu. Providers should have a help file about how to do this, like this one from Hover.
  2. Add a new DNS record, type: CNAME.
  3. Choose a domain name (such as i.example.com) and point it to dl.dropbox.com.

Once the changes have been picked up by the DNS system, you’re done! Your screenshots will be available under a URL like: http://i.example.com/u/XYZ/Screenshots/abcd.png.

While certainly elegant, one (big) caveat of this solution is that the resulting URLs still contain the portion /u/XYZ/Screenshots. Because the CNAME record works purely on a domain level, there is no way for us to hide this portion of the URLs with this method.

"}}

Whole-Genome Sequencing and Social-Network Analysis of a Tuberculosis Outbreak — NEJM

Sunday, July 23rd, 2017

WGS & Social-#Network Analysis of a TB Outbreak http://www.NEJM.org/doi/full/10.1056/NEJMoa1003176 Nice tech combo but not sure transmission & phylogeny are consistent

The Big Short – Wikipedia

Sunday, July 23rd, 2017

Found Lewis’ @theBigShort (https://en.wikipedia.org/wiki/The_Big_Short) v. helpful in understanding the financial plumbing of the ’08 meltdown, eg CDO,CDS,MBS..

How to Deal With North Korea – The Atlantic

Sunday, July 23rd, 2017

https://www.theatlantic.com/amp/article/528717/