Archive for June, 2016

RNA splicing is a primary link between genetic variation and disease | Science

Wednesday, June 15th, 2016

http://science.sciencemag.org/content/352/6285/600.long

DNA: ‘The Power of the Beautiful Experiment’ by H. Allen Orr | The New York Review of Books

Monday, June 13th, 2016

The Power of the Beautiful Experiment
http://www.nybooks.com/articles/2016/06/09/dna-power-beautiful-experiment/ highlights greater success of expt vs theory in cracking the genetic code

How does multiple testing correction work?

Monday, June 13th, 2016

How does multiple-testing correction work
http://www.nature.com/nbt/journal/v27/n12/abs/nbt1209-1135.html Intuition for teaching: genome-wide error rate on a single gene v family

Turtles all the way down – Wikipedia, the free encyclopedia

Monday, June 13th, 2016

https://en.wikipedia.org/wiki/Turtles_all_the_way_down

The role of regulatory variation in complex traits and disease : Nature Reviews Genetics : Nature Publishing Group

Sunday, June 12th, 2016

Reg. variation in cplx traits by @LeonidKruglyak
http://www.nature.com/nrg/journal/v16/n4/full/nrg3891.html nice teaching figure for #eQTLs, showing how mostly cis + hotspots http://www.nature.com/nrg/journal/v16/n4/full/nrg3891.html

Photo 51 – Wikipedia, the free encyclopedia

Sunday, June 12th, 2016

QT:{{”

Photograph 51 is the nickname given to an X-ray diffraction image of DNA taken by Raymond Gosling in May 1952, working as a PhD student under the supervision of Rosalind Franklin,[1][2][3][4] at King’s College London inSir John Randall’s group. It was critical evidence[5] in identifying the structure of DNA.[6]

James Watson was shown the photo by Maurice Wilkins without Rosalind Franklin’s approval or knowledge (although by this time Gosling had returned to the supervision of Wilkins). Along with Francis Crick, Watson used characteristics and features of Photo 51 to develop the chemical model of the DNA molecule. In 1962, the Nobel Prize in Physiology or Medicine was awarded to Watson, Crick and Wilkins. The prize was not awarded to Franklin; she had died four years earlier, and the Nobel Prize’s rules require that it be awarded only to living persons.[7]

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https://en.wikipedia.org/wiki/Photo_51

Rosalind Franklin – Wikipedia, the free encyclopedia

Sunday, June 12th, 2016

https://en.wikipedia.org/wiki/Rosalind_Franklin

Martin Niemöller: “First they came for the Socialists…”

Sunday, June 12th, 2016

https://www.ushmm.org/wlc/en/article.php?ModuleId=10007392

Comparison of Nazism and Stalinism – Wikipedia, the free encyclopedia

Sunday, June 12th, 2016

QT:{{”
Creating the “New Man”
Both Stalinism and Nazism share an ideological vision of creating an ideal “new man”, both identified the “bourgeois” world as the old world that was obsolete, and both involved a total rejection of liberalism as well as individual rights and freedoms, in which they sought to create a new, illiberal modern society.[34][35] This vision of the New Man differed between them, the Stalinists conceived of the New Man as necessarily involving the liberation of all of humanity – a global and non-ethnic goal, while the Nazis conceived of the New Man as a master race that would organize a new racial hierarchy in Europe.[34] Both systems made heavy use of propaganda, with Stalinism attempting to reshape the new “Soviet man”.[36]
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role of Lysenko in this…

https://en.wikipedia.org/wiki/Comparison_of_Nazism_and_Stalinism

Twin study – Wikipedia, the free encyclopedia

Sunday, June 12th, 2016

particular favorite in WWII

https://en.wikipedia.org/wiki/Twin_study