Archive for February, 2015

Cite Cost of Sequencing Graphs

Saturday, February 21st, 2015

The Sboner et al. “cost of sequencing” graphs
(http://papers.gersteinlab.org/papers/costseq) have been cited frequently in the biotech industry. Here are a few examples :

This GE Health Care lecture (no direct cite)
https://www.youtube.com/watch?v=NNeKaSQKiM8 at ~13:30

This white paper by EMC:
http://www.emc.com/collateral/white-papers/h10642-cost-per-base-wp.pdf

When G.M. Was Google – The New Yorker

Saturday, February 21st, 2015

http://www.newyorker.com/magazine/2014/12/01/g-m-google

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Saturday, February 21st, 2015

Human & mouse [mRNA] #methylomes revealed by m6A-seq http://www.nature.com/nature/journal/v485/n7397/full/nature11112.html Conservation across species & conditions (for most sites)

Dan Dominissini,
Sharon Moshitch-Moshkovitz,
Schraga Schwartz,

Rotem Sorek
& Gideon Rechavi

Nature 485, 201–206 (10 May 2012) doi:10.1038/nature11112

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators : Nature : Nature Publishing Group

Saturday, February 21st, 2015

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators http://www.nature.com/nature/journal/v508/n7497/full/nature13206.html Reconstructed #evolution across 8 species

Daniel W. Bellott,
Jennifer F. Hughes,

Richard A. Gibbs,
Richard K. Wilson
& David C. Page

Nature 508, 494–499 (24 April 2014) doi:10.1038/nature13206

Space-time wiring specificity supports direction selectivity in the retina : Nature : Nature Publishing Group

Saturday, February 21st, 2015

Spacetime wiring specificity supports…selectivity in the retina http://www.nature.com/nature/journal/v509/n7500/full/nature13240.html @eye_wire citizenscience traces neural connectivity

http://blog.eyewire.org/en/

finds a time lag circuit

Jinseop S. Kim,
Matthew J. Greene,

H. Sebastian Seung
& the EyeWirers

Nature 509, 331–336 (15 May 2014) doi:10.1038/nature13240

High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program

Saturday, February 21st, 2015

High-res mapping reveals a conserved…mRNA methylation program http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956118/ Predicting methyl sites w/ seq., structure & position

Cell. 2013 Dec 5; 155(6): 1409–1421.
Published online 2013 Nov 21. doi: 10.1016/j.cell.2013.10.047 PMCID: PMC3956118
NIHMSID: NIHMS550466

High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program

Schraga Schwartz,1,* Sudeep D. Agarwala,2,* Maxwell R. Mumbach,1 Marko Jovanovic,1 Philipp Mertins,1 Alexander Shishkin,1 Yuval Tabach,3,4 Tarjei S Mikkelsen,1 Rahul Satija,1 Gary Ruvkun,3,4 Steven A. Carr,1 Eric S. Lander,1,5,6 Gerald R. Fink,1,2,8 and Aviv Regev 1,7,8

Glossary Term: Key Opinion Leader (KOL)

Saturday, February 21st, 2015

http://www.pharma-mkting.com/glossary/keyopinionleader.htm

Project Sheds Light on What Drives Genes – NYTimes.com

Friday, February 20th, 2015

http://www.nytimes.com/2015/02/19/health/scientists-shed-light-on-circuits-that-control-genes.html?_r=0

Privacy in Pharmacogenetics: An End-to-End Case Study of Personalized Warfarin Dosing | USENIX

Friday, February 20th, 2015

Privacy in Pharmacogenetics…Personalized Warfarin Dosing
https://www.usenix.org/conference/usenixsecurity14/technical-sessions/presentation/fredrikson_matthew Model-inversion attack; differential privacy doesn’t help

Authors:
Matthew Fredrikson, Eric Lantz, and Somesh Jha, University of Wisconsin—Madison; Simon Lin, Marshfield Clinic Research Foundation; David Page and Thomas Ristenpart, University of Wisconsin—Madison

Awarded Best Paper!

Article for you

Wednesday, February 18th, 2015

http://mobile.nytimes.com/2015/02/16/opinion/the-clutter-cures-illusory-joy.html?_r=0&referrer=