Archive for January, 2015

No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans : Nature Genetics : Nature Publishing Group

Sunday, January 18th, 2015

Removing deleterious mutations in Europeans [v] Africans
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3186.html Comparing nonsynonymous freq. betw. populations HT @obahcall

Gil Amelio – Wikipedia, the free encyclopedia

Saturday, January 17th, 2015

There for ODYSSEUS’ RETURN TO ITHACA

http://en.m.wikipedia.org/wiki/Gil_Amelio

Do I Really Need Regular Checkups at the Dentist and Doctor?

Saturday, January 17th, 2015

Do I Really Need Regular Checkups at the… Doctor?
http://lifehacker.com/do-i-really-need-regular-checkups-at-the-dentist-and-do-1491777950 Juxtaposed against the opposing view, viz:
http://www.nytimes.com/2015/01/09/opinion/skip-your-annual-physical.html

Other article:
Skip Your Annual Physical – NYTimes.com

Avie Tevanian – Wikipedia, the free encyclopedia

Saturday, January 17th, 2015

responsible for the next in mac osx
http://en.m.wikipedia.org/wiki/Avie_Tevanian

Laurene Powell Jobs – Wikipedia, the free encyclopedia

Saturday, January 17th, 2015

http://en.m.wikipedia.org/wiki/Laurene_Powell_Jobs

Motorola S305 Manual

Saturday, January 17th, 2015

http://www.motorola.com/moto_care/manuals/S305_QSG.pdf

Emerging landscape of oncogenic signatures across human cancers

Saturday, January 17th, 2015

Landscape of oncogenic signatures across human #cancers
http://www.nature.com/ng/journal/v45/n10/full/ng.2762.html Disjoint types dominated by copy number changes or mutations

pp1127 – 1133

Giovanni Ciriello, Martin L Miller, Bülent Arman Aksoy, Yasin Senbabaoglu, Nikolaus Schultz & Chris Sander

doi:10.1038/ng.2762

Chris Sander and colleagues have extracted significant functional events from 12 tumor types. Tumors can be classified as being driven largely by either mutation or copy number changes, and, within this division, subclasses of cross-tissue patterns of events are discerned that suggest sets of combinatorial therapies.

Genentech Redux? Roche Buys Majority Stake in Foundation Medicine | Xconomy

Friday, January 16th, 2015

http://www.xconomy.com/boston/2015/01/12/genentech-redux-roche-buys-majority-stake-in-foundation-medicine/

Why I Hope to Die at 75

Friday, January 16th, 2015

Why I Hope to Die at 75 http://www.theatlantic.com/features/archive/2014/09/why-i-hope-to-die-at-75/379329 Noted #bioethicist’s view on lifespan. Let’s see if he practices what he preaches.

Book Review: ‘The Patient Will See You Now’ by Eric Topol – WSJ

Monday, January 12th, 2015

http://www.wsj.com/articles/book-review-the-patient-will-see-you-now-by-eric-topol-1421106779