Archive for November, 2014

Nuclear reaction

Saturday, November 22nd, 2014

Nuclear reaction
http://www.economist.com/news/science-and-technology/21630959-how-complex-cells-evolved-mystery-new-idea-may-come-close Hypothesis from BMC paper on #evolution of eukaryotes from membrane blebs (http://www.biomedcentral.com/1741-7007/12/76)

An inside-out origin for the eukaryotic cell

David A Baum and Buzz Baum

BMC Biology 2014, 12:76 doi:10.1186/s12915-014-0076-2

QT:{{”

The consensus is that the first eukaryote was a prokaryote which engulfed, but failed on several occasions to digest, other
prokaryotes. One of these undigested meals was a bacterium ancestral to mitochondria. Even today mitochondria have their own genes separate from those in the nucleus. These genes, which are carried on circular DNA molecules like those in bacteria, resemble those in a group of bacteria called Rickettsiales,

They imagine the original host prokaryote creating small protrusions, known to microbiologists as blebs, that poked out of it, as the diagram shows, like tiny fingers. Blebs like this are known to form in certain sorts of archaea, a group of prokaryotes distinct from bacteria proper that biochemical evidence suggests were involved in the formation of eukaryotes. The job of blebs is unclear, as archaea are not a well-studied group, but they may be feeding structures. The Drs Baum suggest that, in the case of the ancestral eukaryote, the blebs grew bigger and bigger, pinning proto-mitochondria (and, on a subsequent occasion, proto-chloroplasts), into the intervening spaces. “}}

The Startup That Lets You Communicate from Beyond the Grave | WIRED

Friday, November 21st, 2014

http://www.wired.com/2014/11/talking-to-the-dead/

SVS: Aquarius Sea Surface Salinity 2011-2014 – Rotating Globes (id 4234)

Friday, November 21st, 2014

Sea Surface Salinity http://svs.gsfc.nasa.gov/cgi-bin/details.cgi?aid=4234 Dramatic differences between Atlantic & Pacific, reflecting local rainfall HT ‏@coreyspowell

QT:{{"
@coreyspowell :
The saltiest (& least salty) waters in the world–a clever way to
track rainfall & climate. http://1.usa.gov/1q1UEoj

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Twitter “Exhaust” Reveals Patterns of Unemployment | MIT Technology Review

Friday, November 21st, 2014

http://www.technologyreview.com/view/532746/twitter-exhaust-reveals-patterns-of-unemployment/

A case study for cloud based high throughput analysis of NGS data using the globus genomics system

Friday, November 21st, 2014

http://www.sciencedirect.com/science/article/pii/S2001037014000427

crowd-powered text editing

Friday, November 21st, 2014

https://wordy.com/ — not exactly but in the same space.
turk-powered “Shortn” app, which is actually part of a larger system called soylent (brilliant).
http://people.csail.mit.edu/msbernst/research.html

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer

Thursday, November 20th, 2014

Dataset of 100 freely available STAD T/N pairs

http://www.nature.com/ng/journal/v46/n6/full/ng.2983.html#affil-auth

Kai Wang,
Siu Tsan Yuen,
Jiangchun Xu,
Siu Po Lee,
Helen H N Yan,
Stephanie T Shi,
Hoi Cheong Siu,
Shibing Deng,
Kent Man Chu,
Simon Law,
Kok Hoe Chan,
Annie S Y Chan,
Wai Yin Tsui,
Siu Lun Ho,
Anthony K W Chan,
Jonathan L K Man,
Valentina Foglizzo,
Man Kin Ng,
April S Chan,
Yick Pang Ching,
Grace H W Cheng,
Tao Xie,
Julio Fernandez,
Vivian S W Li,
Hans Clevers,
Paul A Rejto,
Mao Mao
& Suet Yi Leung

Nature Genetics 46, 573–582 (2014) doi:10.1038/ng.2983Received 01 August 2013 Accepted 18 April 2014 Published online 11 May 2014

What the shape of our cities says about the way that we live – Salon.com

Monday, November 17th, 2014

http://www.salon.com/2014/11/16/what_the_shape_of_our_cities_says_about_the_way_that_we_live/?utm_source=twitter&utm_medium=socialflow

A Brief History of Failure – NYTimes.com

Sunday, November 16th, 2014

http://www.nytimes.com/interactive/2014/11/12/magazine/16innovationsfailures.html?smid=tw-nytimes

Why Are So Few Blockbuster Drugs Invented Today? – NYTimes.com

Sunday, November 16th, 2014

http://www.nytimes.com/2014/11/16/magazine/why-are-there-so-few-new-drugs-invented-today.html?partner=rss&emc=rss&_r=2&utm_content=buffercce9a&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer