Archive for December, 2013

cancer eQTL

Tuesday, December 17th, 2013

germline eQTLs vs somatic contributions

Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci Cell , 2013

http://www.sciencedirect.com/science/article/pii/S0092867412015565

also

GWAS Meets TCGA to Illuminate Mechanisms of Cancer Predisposition http://www.sciencedirect.com/science/article/pii/S0092867413000792

Underrated Apps – Business Insider

Tuesday, December 17th, 2013

IFTTT is a super-cool product – it effectively lets you play with API access (like Twitter or Facebook) without actually trying to figure out the mess that is most APIs.

http://www.businessinsider.com/underrated-apps-2013-12#ifttt-syncs-apps-together-to-create-powerful-multi-tasking-concoctions-2

House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus infection

Tuesday, December 17th, 2013

http://www.pnas.org/content/early/2013/12/13/1310750111.abstract

Worried baby will develop asthma/allergies? Get a dog: alter gut microbiome–> protection vs both (at least in mice)
@sxbegle will this work for cats too?! goldfish?

The role of replicates for error mitigation in next-generation sequencing

Monday, December 16th, 2013

http://www.nature.com/nrg/journal/vaop/ncurrent/full/nrg3655.html

on the various sources of errors in NGS and the role of replicates in reducing errors:

Use of ontologies in RNAseq data analysis

Monday, December 16th, 2013

came across this paper: http://genomebiology.com/content/11/2/R14, which uses GO for RNA-seq data analysis
looks interesting – GoSeq !

glasses.com for iPhone on the App Store on iTunes

Monday, December 16th, 2013

“This amazing iPhone app 3D models your face and let’s you try glasses on your own face! ”

https://itunes.apple.com/us/app/glasses.com-for-iphone/id738159996

Five Web-based Apps to help you visualize big data – TechRepublic

Monday, December 16th, 2013

Five Web-based Apps to help you #visualize big data: Many Eyes, ICharts, Visualize Free, Wolfram Alpha, Data Wrangler
http://www.techrepublic.com/blog/five-apps/five-web-based-apps-to-help-you-visualize-big-data ==
Also Visualize Free to complete the 5 MT @KirkDBorne 5 Web-based Apps to help you visualize #BigData
http://www.techrepublic.com/blog/five-apps/five-web-based-apps-to-help-you-visualize-big-data

Why Everyone Will Totally Read This Column – WSJ.com

Monday, December 16th, 2013

Sort of like buZz feed….
http://m.us.wsj.com/articles/SB10001424052702304579404579231772007379090

Snacking Your Way to Better Health – NYTimes.com

Monday, December 16th, 2013

http://well.blogs.nytimes.com/2013/12/09/snacking-your-way-to-better-health/?ref=health&smid=tw-nytimes&_r=0

Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution

Sunday, December 15th, 2013

QT:{{”
We found that ~15% of human codons are dual-use codons (“duons”) that simultaneously specify both amino acids and TF recognition sites. Duons are highly conserved and have shaped protein evolution, and TF-imposed constraint appears to be a major driver of codon usage bias.
“}}

http://www.sciencemag.org/content/342/6164/1325.summary
http://www.sciencemag.org/content/342/6164/1367.abstract