linkstream2 microblog

Interesting discussion of a temporal cloaking device that can hide picosecond timescales. This could potentially be used to obscure communication between two parties — from say the CIA — in a short time period.

Temporal cloak erases data from history. Perhaps useful to foil future #NSA metadata collection.
http://www.nature.com/news/temporal-cloak-erases-data-from-history-1.13141 #privacy

http://www.nature.com/news/temporal-cloak-erases-data-from-history-1.13141

Further compacted apx evening #traintimes for #NHV=>#NYC: (4-10):45 #Mnr, [589]:10 #Amtrak, [67]:20 A, 5:30 M, (11-12):35 MA

MNR departures

4:47 PM
5:33 PM
5:52 PM
6:53 PM
7:55 PM
8:48 PM
9:45 PM
10:45 PM
11:35 PM

Amtrak Departures

5:16pm – 6:45pm
2171 Acela Express

6:19pm – 7:45pm
2173 Acela Express

7:27pm – 8:55pm
2175 Acela Express

8:14pm – 9:50pm
177 Northeast Regional

9:12pm – 10:45pm
179 Northeast Regional

12:35am – 2:15am
67 Northeast Regional

Updated NHV=>NYC for (M)nr, amtrak (R)egional & (A)cela evening trains: 530 M, [56789,10]:45 M, [67]:20 A, [89]:10 R, 1135 M, 1235 R

MNR departures

4:47 PM
5:33 PM
5:52 PM
6:53 PM
7:55 PM
8:48 PM
9:45 PM
10:45 PM
11:35 PM

Amtrak Departures

6:19pm – 7:45pm
2173 Acela Express

7:27pm – 8:55pm
2175 Acela Express

8:14pm – 9:50pm
177 Northeast Regional

9:12pm – 10:45pm
179 Northeast Regional

12:35am – 2:15am
67 Northeast Regional

The opposite of clique completion: #Network deconvolution.. to distinguish direct dependencies http://go.nature.com/dVzNwC via @taziovanni

Network deconvolution as a general method to distinguish direct dependencies in networks

Soheil Feizi, Daniel Marbach, Muriel Médard & Manolis Kellis

http://www.nature.com/nbt/journal/vaop/ncurrent/full/nbt.2635.html

My thoughts:

Indirect relationships in a network can confound the inference of true direct relationships in a network. T, so this paper sought to develop a quantitative framework, termed network deconvolution (ND), to infer direct relationships and remove false positives in a network by quantifying and then removing indirect transitive relationship effects. The mathematical framework assumes that (1) an indirect relationship (edge) can be approximated as the product of its component direct edges and that (2) the observed edge weights are the sum of the direct and indirect edge weights – a linear dependency. The main application seems to be in mutual information (MI) and
correlation-based (COR) networks. They applied ND to various scenarios such as local network connectivity prediction (FFL
prediction), gene regulatory network prediction (in E. coli), prediction of interacting amino acids in protein structures (MI network) and coauthorship relationship network and found that (1) it can be used with various networks beyond just MI and COR (2) it can be used alone or more powerfully in combination with existing
methods/algorithms to improve predictions. In a sense it is the opposite of clique and module completion approaches (such as k-core).

From Mars.. adventures in women’s #publishing: Why many writing cheaply beats a few pricey articles. nyr.kr/1b2n9sW MT @peterjblack

VIZ:

Interesting discussion of the economics of web publishing: why it’s better to get lots of people to cheaply write articles than rely on a few well written but expensive pieces

From Mars: A young man’s adventures in women’s publishing.
http://www.newyorker.com/reporting/2013/09/23/130923fa_fact_widdicombe

QT:”
By the time it was sold to Turner, Bleacher Report was making tens of millions of dollars a year. Brian Morrissey, the editor of Digiday, recently explained how publishers like Bleacher Report have managed to succeed by “gaming the Internet ad system.” Advertising on the Web is cheap: Bleacher Report charges roughly fifty dollars for every thousand people who see their most expensive type of ad, a “homepage takeover.” Meanwhile, Sports Illustrated, whose circulation is three million, charges almost four hundred thousand dollars for a full-page color ad. But, Morrissey said, “You make up for low ad rates by producing as many page views as possible at low costs.” A
well-researched exposé, such as the one Sports Illustrated recently ran about N.C.A.A. violations by the Oklahoma State football team, may take many months of work from a highly paid reporter and editor. But, in the end, Morrissey said, “it yields the same revenue as a ‘25 Sexiest Female Athletes Who Can Kick Your Ass’ post, which costs, like, two hundred dollars.”
“

Interesting but dated read. Discusses how hThe Future of Man @sciam: Interesting but dated; how humans are anti-evolving because of medicine http://www.scientificamerican.com/article.cfm?id=the-future-of-man #evolution

http://www.scientificamerican.com/sciammag/?contents=2009-jan

Interesting discussion of how to tell apart classical and quantum systems using Bells inequality. The basic idea is finding more correlated events between two separate
systems than one might expect classically were they are decoupled. This implies that there is a quantum characteristic to the system. This fact can be exploited to measure the degree to which two systems are behaving as a “quantum unit” in relation to cryptographic applications and large-scale quantum
computation.

http://www.nature.com/nature/podcast/v496/n7446/nature-2013-04-25.html

#Quantum physics: A grip on misbehaviour – explains how Bell’s inequality quantifies #entanglement
http://www.nature.com/nature/journal/v496/n7446/full/496436a.html #QM

Amazing #Images of urban decay – Ephemeral Tour of Europe’s Abandoned Industrial #Ruins
http://gizmodo.com/an-ephemeral-tour-of-europes-abandoned-industrial-ruin-1173257449 MT @mpitchford
http://gizmodo.com/an-ephemeral-tour-of-europes-abandoned-industrial-ruin-1173257449

Great link on True Cost of Science #Publishing: $5K/article with #openaccess giving clearer view on costs
http://www.nature.com/news/open-access-the-true-cost-of-science-publishing-1.12676 MT @Richvn

Interesting discussion on the cost of scientific publishing. It appears that the open access model, in addition to having free access to the content, is also giving people a much more open view of the cost. This is because most of the costs are upfront and clear to see author paid charges as opposed to being hidden in secret contracts to libraries. A number of the journals have a cost of
~$5000/article going down to as low as ~$1300 for PLoS ONE.
It is claimed that some of the marquee subscription
publishers such as Nature have costs of >$30,000/article
and it is interesting thinking about how to meld these
together.

Nature: A gene of rare effect. Interesting discussion of #PCSK9 as a poster child for #LOF mutations
http://www.nature.com/news/genetics-a-gene-of-rare-effect-1.12773 #genetics

The woman who had this LOF mutation was identified in the large Dallas cholesterol study based on her family history.

QT:”
How did the gene exert such profound effects on LDL cholesterol levels? As researchers went on to determine, the PCSK9 protein normally circulates in the bloodstream and binds to the LDL receptor, a protein on the surface of liver cells that captures LDL cholesterol and removes it from the blood. After binding with the receptor, PCSK9 escorts it into the interior of the cell, where it is eventually degraded. When there is a lot of PCSK9 (as in the French families), there are fewer LDL receptors remaining to trap and remove bad cholesterol from the blood. When there is little or no PCSK9 (as in the black people with mutations), there are more free LDL receptors, which in turn remove more LDL cholesterol.
“