Posts Tagged ‘signaling’

Linking signaling pathways to transcriptional programs in breast cancer

Friday, March 20th, 2015

Linking #signaling pathways [phospho-proteins in samples] to transcriptional programs [TFs & targets], via matrices
http://genome.cshlp.org/content/24/11/1869.long

More verbosely:
using matrices to linking TF & targets and phosphorsylated proteins in particular samples to gene expression in specific samples

Linking signaling pathways to transcriptional programs in breast cancer

Hatice U. Osmanbeyoglu1,
Raphael Pelossof1,
Jacqueline F. Bromberg2 and
Christina S. Leslie1

Genome Research

How Information Theory Handles Cell Signaling and Uncertainty

Tuesday, February 4th, 2014

Matthew D. Brennan, Raymond Cheong, and Andre Levchenko

Science. 2012 October 19; 338(6105): 10.1126/science.1227946. doi: 10.1126/science.1227946
PMCID: PMC3820285
NIHMSID: NIHMS512743

How Information Theory Handles #Cell Signaling & Uncertainty… really well since it’s ideal for noisy communication
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820285/?report=classic