Posts Tagged ‘#massspec’

number of transcription factor molecules per cell

Thursday, March 6th, 2014

System-wide analyses have underestimated #protein abundances… Corrected protein conc. better correlated w/ #mRNA

…once a non linear bias in mass spec. data is corrected, the concentration of the factor expressed at the median level is present at 70,000 molecules per cell. ….

Li, J, Bickel, P.J. and Biggin M.D. (2014) System Wide Analyses have Underestimated Protein Abundances and the Importance of Transcription in Mammals. PeerJ DOI10.7717/peerj.270