linkstream2 microblog

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Yellapragada Subbarow (12 January 1895 – 8 August 1948) was an Indianbiochemist who discovered the function of adenosine triphosphate as an energy source in the cell, and developed methotrexate for the treatment of cancer. Most of his career was spent in the United States. Despite his isolation of ATP, Subbarow was denied tenure at Harvard[1][2] though he would lead some of America’s most important medical research during World War II. Subbarow died in the United States.[3] Subbarow is also credited with the first synthesis of the chemical compounds folic acid and methotrexate.
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https://en.m.wikipedia.org/wiki/Yellapragada_Subbarow

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The human body needs folate to make DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions.[11] It is especially important in aiding rapid cell divisionand growth, such as in infancy and pregnancy. Children and adults both require folate to produce healthy red blood cells and prevent anemia.[12] “}}
https://en.m.wikipedia.org/wiki/Folic_acid

https://en.m.wikipedia.org/wiki/Aminopteri

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Discovered by Dr. Yellapragada Subbarow, the drug was first used by Sidney Farber in 1947 to induce remissions among children with leukemia.[2][3] Aminopterin was later marketed by Lederle Laboratories (Pearl River, New York) in the United States from 1953 to 1964 for the indication of pediatric leukemia. The closely related antifolate methotrexate was simultaneously marketed by the company during the same period. Aminopterin was discontinued by Lederle Laboratories in favor of methotrexate due to manufacturing difficulties…
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Early report of cancer
https://en.m.wikipedia.org/wiki/Atossa

Anti folate
https://en.m.wikipedia.org/wiki/Aminopterin

https://en.m.wikipedia.org/wiki/Sidney_Farber

https://en.m.wikipedia.org/wiki/Hyperplasia

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Hyperplasia (from ancient Greek ὑπέρ huper, “over” + πλάσις plasis, “formation”), or hypergenesis, is an increase in the amount of organic tissue that results from cell proliferation.[1] It may lead to the gross enlargement of an organ and the term is sometimes confused with benignneoplasia or benign tumor.[2]
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4 of them

https://en.m.wikipedia.org/wiki/Humorism

https://www.wordnik.com/words/onkos

https://en.m.wikipedia.org/wiki/Joseph_Lister,_1st_Baron_Lister