BMC Genomics | Abstract | Assessing structural variation in a personal genome—towards a human reference d iploid genome
Monday, May 4th, 2015consensus method
Archive for the ‘SciLit’ Category
Genome Biology | Full text | An integrative probabilistic model for identification of structural variation in sequencing data
Monday, May 4th, 2015QT:{{”
We introduce GASVPro, an algorithm combining both paired read and read depth signals into a probabilistic model that can analyze multiple alignments of reads.
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Characterization of structural variants with single molecule and hybrid sequencing approaches
Monday, May 4th, 2015QT:{{”
We present MultiBreak-SV, an algorithm to detect structural variants (SVs) from single molecule sequencing data, paired read sequencing data, or a combination of sequencing data from different platforms. “}}
uses pacbio
http://bioinformatics.oxfordjournals.org/content/30/24/3458.long
Longitudinal analysis of microbial interaction between humans and the indoor environment
Sunday, May 3rd, 2015Microbial interaction betw humans & the indoor environment http://www.sciencemag.org/content/345/6200/1048.abstract
Unique personal signatures w/ implications for #forensics
Places change to conform to signature…..
The evolutionary history of lethal metastatic prostate cancer : Nature : Nature Publishing Group
Saturday, May 2nd, 2015The evolutionary history of…metastatic prostate #cancer http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14347.html Unexpected: polyclonal "seeding" w/ much met-to-met spread
Reverse-engineering censorship in China: Randomized experimentation and participant observation
Saturday, May 2nd, 2015Reverse-engineering #censorship in #China: Randomized expts
http://www.sciencemag.org/content/345/6199/1251722.abstract Criticism is ok but calls for collective action are not
Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage
Saturday, May 2nd, 2015Transmissible Dog #Cancer #Genome Reveals…History of…Cell Lineage http://www.sciencemag.org/content/343/6169/437.abstract 1.9M somatic mutations from origin ~11K yrs ago
Can disparities be deadly?
Tuesday, April 28th, 2015Can disparities be deadly? http://www.sciencemag.org/content/344/6186/829.summary
Correlation v causation: does high government rank lead to good health or the converse
For the famous Whitehall study
Automated validation of genetic variants from large databases: ensuring that variant references refer to the same genomic locations
Sunday, April 26th, 2015Some initial comparisons of HGMD & OMIM, nice to incl. ClinVar in the future