linkstream2 microblog

https://en.wikipedia.org/wiki/Tamoxifen
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In the late 1950s, pharmaceutical companies were actively researching a newly discovered class of anti-estrogen compounds in the hope of developing a morning-after contraceptive pill. Arthur L Walpole was a reproductive endocrinologist who led such a team at the Alderley Park research laboratories of ICI Pharmaceuticals. It was there in 1966 that Dora Richardson first synthesised tamoxifen, known then as ICI-46,474.[59] Walpole and his colleagues filed a UK patent covering this compound in 1962, but patent protection on this compound was repeatedly denied in the US until the 1980s.[60]

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https://en.wikipedia.org/wiki/Elwood_V._Jensen

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In 2004 he received the Albert Lasker Award for Basic Medical Research for his research on estrogen receptors. He is considered the father of the field of hormone action.[1]

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http://www.webmd.com/prostate-cancer/news/20090612/prostate-cancer-who-needs-chemical-castration

chemical castration

https://en.wikipedia.org/wiki/Charles_Brenton_Huggins

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Charles Brenton Huggins (September 22, 1901 – January 12, 1997) was a Canadian-American physician, physiologist and cancer researcher at theUniversity of Chicago specializing in prostate cancer. He was awarded the 1966 Nobel Prize for Physiology or Medicine for discovering in 1941 thathormones could be used to control the spread of some cancers.[1] This was the first discovery that showed that cancer could be controlled by chemicals.
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prostate cancer

https://en.wikipedia.org/wiki/Cisplatin

https://news.google.com/newspapers?nid=1301&dat=19740528&id=qgtiAAAAIBAJ&sjid=a-UDAAAAIBAJ&pg=5129,9648489&hl=en

Stewart Alsop & Cancer

http://www.texascancercenter.com/cancerhistory.html
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This theory of "centrifugal spread" became the foundation of surgical oncology. We now know that this theory was wrong. Cancer does spread to distant organs primarily through the blood stream. But Halsted’s great reputation at the time meant acceptance of his ideas as holy writ.

This flawed perception of tumor spread supported aggressive surgical treatment. Surgeons believed that if the tumor could be surrounded and removed the patient could be cured. The "centrifugal spread" theory meant that cure was totally in the hands of their surgeon

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https://onlinecourses.science.psu.edu/stat414/node/307

development of statistical power

http://saatchibill.tumblr.com/post/82180619294/the-word-lumpectomy-was-a-surgeons-insult#.V9Vs85MrKXQ

Keynes

http://www.cancer.gov/about-nci/legislative/history/national-cancer-act-1971