linkstream2 microblog

http://www.texascancercenter.com/cancerhistory.html
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This theory of "centrifugal spread" became the foundation of surgical oncology. We now know that this theory was wrong. Cancer does spread to distant organs primarily through the blood stream. But Halsted’s great reputation at the time meant acceptance of his ideas as holy writ.

This flawed perception of tumor spread supported aggressive surgical treatment. Surgeons believed that if the tumor could be surrounded and removed the patient could be cured. The "centrifugal spread" theory meant that cure was totally in the hands of their surgeon

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https://onlinecourses.science.psu.edu/stat414/node/307

development of statistical power

http://saatchibill.tumblr.com/post/82180619294/the-word-lumpectomy-was-a-surgeons-insult#.V9Vs85MrKXQ

Keynes

http://www.cancer.gov/about-nci/legislative/history/national-cancer-act-1971

https://en.wikipedia.org/wiki/Chappaquiddick_incident

had an impact on ’70s cancer research

https://en.wikipedia.org/wiki/The_Selfish_Gene

https://en.wikipedia.org/wiki/Rous_sarcoma_virus

RSV causes cancer

http://scienceblog.cancerresearchuk.org/2014/08/27/mustard-gas-from-the-great-war-to-frontline-chemotherapy/

http://www.nejm.org/doi/full/10.1056/NEJM199310283291801#t=article

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When treated with effective multiagent chemotherapy, about two thirds of children with newly diagnosed acute lymphoblastic leukemia survive for long periods of time1-4. Much of this success can be credited to more intensive early treatment, especially of patients at higher risk of relapse.
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Result of Pinkel ’79 study

http://flip.it/S0H5lK